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Enzymatic Formation of Leukotrienes

  • Barbara A. Jakschik
  • Christine G. Kuo
  • Yue Fang Wei
Part of the Prostaglandins, Leukotrienes, and Cancer book series (PLAC, volume 1)

Abstract

Release of slow reacting substance (SRS) from guinea pig lung treated with cobra venom was described in 1938 (1) and release due to immunological challenge in 1940 (2). Characterization of SRS showed that it was a polar lipid with absorbance in the UV region and that it might contain sulfur (3–6). Work with labeled arachidonic acid indicated that this fatty acid is a metabolic precursor of SRS (7,8).

Keywords

Calcium Ionophore A23187 Sucrose Pellet Eicosatrienoic Acid Eicosatetraenoic Acid Polyenoic Fatty Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1985

Authors and Affiliations

  • Barbara A. Jakschik
  • Christine G. Kuo
  • Yue Fang Wei

There are no affiliations available

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