Alterations in Fatty Acid Composition of Phospholipids in Heart Muscle Induced by Various Forms of Stress
Stress is considered one of the pathogenic factors in development of coronary artery disease. Increased sympathetic activity and elevated plasma levels of catecholamines influence markedly cardiac function and myocardial metabolism. Changes in function of the heart induced by exogenous or endogenous catecholamines during stress or significant changes in living conditions could modify composition of membrane lipids during the process of adaptation. Catecholamines have been shown to affect various aspects of glycerolipid metabolism (1).
KeywordsLinoleic Acid Fatty Acid Composition Arachidonic Acid Ventricular Fibrillation Docosahexaenoic Acid
Unable to display preview. Download preview PDF.
- 3.Gudbjarnason, S., Emilsson, A. and Gudmundsdóttir, A. Fatty acid composition of phospholipids of heart muscle in relation to age, dietary fat and stress. In: H. Peeters, G.A. Gresham and R. Paoletti (ed). Arterial Pollution.Plenum Publ. Corp. 1983, pp. 115–124.Google Scholar
- 5.Daves, G.S. Foetal and Neonatal Physiology. Year Book, Medical Publishers, Inc., Chicago, 1969.Google Scholar
- 6.Gudbjarnason, S., Whitehurst, V., Simental, F. and Balazs, T. Alterations in fatty acid composition of phospholipids in rat heart muscle during weight loss and increased resistance to cardiotoxicity of isoproterenol. The Toxicologist 4: pp. 77, 1984.Google Scholar
- 7.Johnson, G.L., El-Hage, A., Ehrreich, S.I., Gudbjarnason, S., Whitehurst, V. and Balazs, T. Effects of benoxaprofen, diethylcarbamazine or nordihydroguaiaretic acid on isoproterenol induced ventricular fibrillation in rats. Federation Proceedings 43: pp. 742, 1984.Google Scholar
- 8.Johnson, G.L., El-Hage, A., Ehrreigh, S.I., Gudbjarnason, S., Whitehurst, V. and Balazs, T. A possible role of leukotrienes in isoproterenol induced ventricular fibrillation. In “Prostaglandins and Leukotrienes ’84” Washington D.C., Abstract 251, 1984.Google Scholar