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Noradrenaline Induced Myocardiopathy in Normal and Hypercholesterolaemic Rhesus Monkeys

  • P. L. Wahi
  • R. N. Chakravarti
  • I. S. Anand
  • M. Kumar
  • Madhu Khuller
  • S. K. Bhattacharya
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 46)

Abstract

Acute stress is known to cause endogenous liberation of catecholamines which appear to produce myocardial injury through biochemical and pathological mechanisms (Friedberg, 1963; Schettler, 1970). To elaborate these changes in the human is not easy and, therefore, recourse to experimental studies on laboratory animals has been taken (Rona et al. 1959; Renaud and Godu, 1969; Bhattacharya et al. 1974; Johnsson et al. 1974; Sood and Chakravarti, 1976; Khuller et al. 1982). The present report describes the effects of noradrenaline infusion into normo or hypercholesterolaemic rhesus monkeys to elucidate the biochemical and pathological basis of the myocardial lesions produced.

Keywords

Myocardial Injury Heart Muscle Saline Infusion Control Monkey Intercalate Disc 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Martinus Nijhoff Publishing, Boston 1985

Authors and Affiliations

  • P. L. Wahi
    • 1
  • R. N. Chakravarti
    • 1
  • I. S. Anand
    • 1
  • M. Kumar
    • 1
  • Madhu Khuller
    • 1
  • S. K. Bhattacharya
    • 1
  1. 1.Departments of Cardiology and Experimental MedicinePostgraduate Institute of Medical Education & ResearchChandigarhIndia

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