Cardiac operations and transfusion requirements

  • J. J. A. M. Van Den Dungen
  • Ch. R. H. Wildevuur
  • W. L. Bayer


The technique of cardiopulmonary bypass (CPB) to support the patient during cardiac surgery can be performed safely nowadays.


Cardiopulmonary Bypass Fresh Freeze Plasma Postoperative Blood Loss Bubble Oxygenator Donor Unit 
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  1. 1.
    Ott DA, Cooley DA: Cardiovascular surgery in Jehovah’s Witnesses. JAMA, 1977; 238: 1256–58.PubMedCrossRefGoogle Scholar
  2. 2.
    Lambert CJ, Marengo Rowe AJ, Leveson JE, Green RH, Thiele JP, Geisler JF, Adam M, Mitchell BF: The treatment of postperfusion bleedings using e-amino caproic acid, cryoprecipitate, fresh frozen plasma and protamine sulphate. Ann Thor Surg, 1979; 28: 440–44.CrossRefGoogle Scholar
  3. 3.
    Hardin SA, Shakorr MA, Guidon AJ: Platelet support for cardiopulmonary bypass surgery. J Thorac Cardiovasc Surg, 1975; 70: 350–53.Google Scholar
  4. 4.
    Gomes MMR, McGoon DC: Bleeding patterns after open heart surgery. J Thorac Cardiovasc Surg, 1970; 60: 87–97.PubMedGoogle Scholar
  5. 5.
    Geralnick HR, Fisher DR: The haemostatic response to open heart operations. J Thorac Cardiovasc Surg, 1971; 61: 909–15.Google Scholar
  6. 6.
    Bachman F, McKenna R, Cole ER, Njafi: The haemostatic mechanism after open heart surgery. J Thorac Cardiovasc Surg, 1975; 70: 76–85.Google Scholar
  7. 7.
    Moriau M, Masure R, Huslet A, Deteys C, Chalant C, Ponlot R, Jaumain P: Haemostasis disorders in open heart surgery with extra corporeal circulation. Vox Sang, 1977; 32: 41–51.PubMedCrossRefGoogle Scholar
  8. 8.
    Kalter RD, Saul ChM, Wetstein L, Sorians C, Reiss RF: Cardiopulmonary bypass associated haemostatic abnormalities. J Thorac Cardiovasc Surg, 1977; 77: 427–35.Google Scholar
  9. 9.
    McKenna R, Bachmann F, Whittaker B, Gilson JR, Weinberg M: The haemostatic mechanism after open heart surgery. J Thorac Cardiovasc Surg, 1975; 70: 298–308.PubMedGoogle Scholar
  10. 10.
    McKenzie FN, Dhall DP, Arfos KE, Nordlund S, Matheson NE: Blood platelet behaviour during and after open heart surgery. Br Med J, 1969; 2: 795–98.PubMedCrossRefGoogle Scholar
  11. 11.
    Kennedy PS, Soles RTh, Storey SS, Viancos JG, Debakey ME: Cardiopulmonary bypass surgery. Arch Surg, 1978; 113: 1429–32.PubMedGoogle Scholar
  12. 12.
    De Leval MR, Hill JD, Mielke JD, Macur MF, Gerbode F: Blood platelets and extracorporeal circulation. J Thorac Cardiovasc Surg, 1975; 69: 144–51.PubMedGoogle Scholar
  13. 13.
    Smith B, Al Omeri M, Melrose DG, Bentall HH: Blood loss after cardiopulmonary bypass. Lancet, 1964; ii: 273–79.CrossRefGoogle Scholar
  14. 14.
    Ten Duis HJ: Intraoperative autotransfusion. Thesis, University of Groningen, 1982.Google Scholar
  15. 15.
    Van den Dungen JJAM, Karliczek GF, Brenken U, Homan van der Heide JN, Wildevuur ChRH: Clinical study of blood trauma during perfusion with membrane and bubble oxygenators. J Thorac Cardiovasc Surg, 1982; 83: 108–16.PubMedGoogle Scholar
  16. 16.
    Moncade S, Vane JR: Arachidonic acid metabolites and the interactions between platelets and blood vessel walls. N Eng J Med, 1979; 300: 1142–47.CrossRefGoogle Scholar
  17. 17.
    Radegran K, Papaconstantinou C: Prostacyclin infusion during cardiopulmonary bypass in man. Thromb Res, 1980; 19: 267–70.PubMedCrossRefGoogle Scholar
  18. 18.
    Longmore DB, Greame Bennett J, Koyle RM, Smith MA, Gregory A, Orivand T, Gones WA: Prostacyclin administration during cardiopulmonary bypass in man. Lancet, 1981; i: 800–3.CrossRefGoogle Scholar
  19. 19.
    Walker ID, Davidson JF, Faichney A, Wheathley DJ, Davidson KC: A double blind study of prostacyclin in cardiopulmonary bypass surgery. Br J Haematol, 1981; 49: 415–23.PubMedCrossRefGoogle Scholar
  20. 20.
    Faichney A, Davidson KC, Wheathly DJ, Davidson JF, Walker ID: Prostacyclin in cardiopulmonary bypass operation. J Thorac Cardiovasc Surg, 1982; 84: 601–8.PubMedGoogle Scholar
  21. 21.
    Fabiani JN, Bunting S, Ferrier E, O’Grady J, Fontane B, Prigent C, Carpentier A, Vane J, Dubost C: Etude clinique de prostacycline dans les circulations extra corporelles; effects sur l’hemodynamique et la coagulation. Arch Mal Coeur, 1982; 75: 241–48.PubMedGoogle Scholar
  22. 22.
    Schrör K, Dauris H, Matzky R, Ohlendorf R: The anti-platelet and cardiovascular actions of a new carbacyclin derivative (ZK 36374) equipotent to PGI, in vitro. Arch Pharmacol, 1981; 316: 252–55.CrossRefGoogle Scholar
  23. 23.
    Boonstra PW, Karliczek GF, Homan van der Heide JN, Wildevuur ChRH: Cardiotomy suction related to type of operation and perfusion time. Submitted for publication.Google Scholar
  24. 24.
    Boonstra PW, van Imhoff GW, Eijsman L, Kootstra GJ, Homan van der Heide JN, Karliczek GF, Wildevuur ChRH: Reduced platelet damage and improved haemostasis after controlled cardiotomy suction during clinical membrane oxygenator perfusions. Submitted for publication.Google Scholar
  25. 25.
    Boonstra PW, Vermeulen FEE, Leusink JA, De Nooy EH, van Zalk A, Soons JBJ, Wildevuur ChRH: Clinical evaluation of the haematological advantage of a membrane oxygenerator over a bubble oxygenator in cardiopulmonary bypasses of long duration (3 hrs.). Submitted for publication.Google Scholar
  26. 26.
    Bayer WL, Coenen WM, Jenkins DC, Zucker ML: The use of blood and blood components in 1769 patients undergoing open-heart surgery. Ann Thorac Surg, 1980; 29: 117–22.PubMedCrossRefGoogle Scholar
  27. 27.
    Chesbro JH, Clements IP, Fuster V: A platelet inhibitor drug trial in coronary artery bypass operations; benefit of preoperative dipyridamole and aspirin therapy on early post-operative vein graft potency. N Engl J Med, 1982; 307: 73–78.CrossRefGoogle Scholar

Copyright information

© Martinus Nijhoff Publishers. Boston/Dordrecht/Lancaster 1985

Authors and Affiliations

  • J. J. A. M. Van Den Dungen
  • Ch. R. H. Wildevuur
  • W. L. Bayer

There are no affiliations available

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