Abstract
Although there has been much recent interest in the use of direct acting vasodilators in the production of elective hypotension for neurosurgery none of these is able to provide ideal hypotensive conditions in all cases. This is because of the wide variation in the type of hypotension required in different neurosurgical procedures. While some may require only moderate degrees of relatively prolonged hypotension others require instantaneous blood pressure control down to extremely low levels. In cases where the cerebral perfusion pressure is to be severely reduced it is essential to use drugs which allow the maintenance of autoregulation at these extremes.
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© 1985 Plenum Press, New York
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Simpson, P.J. (1985). Pharmacology of Drugs Used in Elective Hypotension for Neurosurgery. In: Heuser, D., McDowall, D.G., Hempel, V. (eds) Controlled Hypotension in Neuroanaesthesia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2499-7_1
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DOI: https://doi.org/10.1007/978-1-4613-2499-7_1
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9512-9
Online ISBN: 978-1-4613-2499-7
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