Macrophages and Dendritic Cells in Rheumatic Diseases

  • Øystein Førre
  • Kristian Waalen
  • Jørn Thoen
  • Torstein Hovig

Abstract

The normal synovial membrane is lined by a double layer of synovial lining cells, which form a multilayer in the rheumatoid synovial membrane. The synovial lining cells have previously been classified according to electron microscopic criteria as A and C cells, which have macrophage characteristics, and B cells, which have fibroblast characteristics. This classification has recently been confirmed using monoclonal antibodies specific for monocyte/macrophage and fibroblast antigens.

Keywords

Arthritis Corticosteroid Lipase Prostaglandin PGE2 

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Copyright information

© Plenum Publishing Corporation 1985

Authors and Affiliations

  • Øystein Førre
    • 1
  • Kristian Waalen
    • 2
  • Jørn Thoen
    • 2
  • Torstein Hovig
    • 3
  1. 1.Oslo Sanitetsforenings Rheumatism HospitalOsloNorway
  2. 2.Institute of Immunology and Rheumatology, RikshospitaletThe National HospitalOsloNorway
  3. 3.Institute for Pathology, Electron Microscopic Laboratory, RikshospitaletThe National HospitalOsloNorway

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