Abstract
Two distinct B cell compartments can be identified in rat spleen. The follicles which contain small recirculating B cells which express surface IgM and IgD and the marginal zones, which are populated with static IgM+ve IgD-ve B cells (1,2). Increasing evidence implicates marginal zone B cells in responses to T cell-independent type 2 (TI-2) antigens and recirculating cells in responses to T cell-dependent antigens (3). This paper describes observations which give insight into the development and maturation of the recirculating follicular (RF) B cells and marginal zone (MZ) B cells.
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© 1985 Plenum Press, New York
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MacLennan, I.C.M., Bazin, H., Chassoux, D., Gray, D., Lortan, J. (1985). Comparative Analysis of the Development of B Cells in Marginal Zones and Follicles. In: Klaus, G.G.B. (eds) Microenvironments in the Lymphoid System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2463-8_17
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DOI: https://doi.org/10.1007/978-1-4613-2463-8_17
Publisher Name: Springer, Boston, MA
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