Abstract
It has been shown that there are two different types of Peyer’s patches, jejunal Peyer’s patches (JPP) and ileocecal or ileal Peyer’s patches (IPP) in sheep1. IPP have been proposed to be ‘bursa-equivalent’ lymphoid tissue of sheep and bear some characteristics of the primary lymphoid organ2. Like the bursa of Fabricius of chickens, IPP consist of numerous follicles of B cells whereas T cells account for only less than 1% of total cells. The majority of IPP cells express small amounts of surface IgM (low sIgM+ or slg10)3,4,5.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
J.D. Reynolds and B. Morris. The evolution and involution of Peyer’s patches in fetal and postnatal sheep. Eur. J. Immunol. 13:627 (1983).
H.A. Gerber. Functional studies on gut associated lymphoid tissues. Ph.D. Thesis, Australian National University, Canberra (1979).
J. Reynolds. Peyer’s patches and the ontogeny of B lymphocytes in sheep. In: “The immune system, vol. 1”, C.M. Steinberg and I. Lefkovits, eds., Karger, Basel (1981).
M. Miyasaka and L. Dudler. Differentiation of ovine immature B cells upon exposure to phorbol myristate acetate. Int. Arch. Allergy Appl. Immunol. 74:281 (1984).
M. Miyasaka, L. Dudler, G. Bordmann, W.M. Leiserson, H.A. Gerber, J. Reynolds and Z Trnka. Differentiation of B lympocytes in sheep. I. Phenotypic analysis of ileal Peyer’ patch cells and the demonstration of a precursor population for sIg+ cells in the ileal Peyer’ patches. Immunology, in press.
J.D. Reynolds and B. Morris. The effect of antigen on the development of Peyer’s patches. Eur. J. Immunol. 14:1 (1984).
J.D. Reynolds and R. Pabst. The emigration of lymphocytes from Peyer’s patches in sheep. Eur. J. Immunol. 14:7 (1984).
M. Miyasaka, L. Dudler, R. Pabst and Z. Trnka. Migration of bone marrow lymphocytes in sheep: In situ labelling of bone marrow lymphocytes with fluorescein isothiocyanate. Manuscript in preparation.
J. Reynolds, unpublished observations.
M.-F. Beya, L. Dudler, M. Miyasaka and Z. Trnka. Studies on the differentiation of T lymphocytes in sheep. II. Characterization of anti-pan T monoclonal antibodies. Manuscript in preparation.
M. Miyasaka and Z. Trnka. Sheep as an experimental model for immunology - immunological techniques in vitro and in vivo. In: “Immunological Methods III”, I. Lefkovits and B. Pernis, eds., Academic Press, New York, in press.
M. Miyasaka, I. Heron, L. Dudler, R.N.P. Cahill, L. Forni, T. Knaak and Z. Trnka. Studies on the differentiation of T lymphocytes in sheep. I. Recognition of a sheep T-lymphocyte differentiation antigen by a monoclonal antibody T-80. Immunol. 49:545 (1983).
M.-F. Beya and M. Miyasaka, unpublished observations.
M.L. Rose and F. Malchiodis. Binding of peanut lectin to thymic cortex and germinal centres of lymphoid tissue. Immunol. 42:583 (1981).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Plenum Press, New York
About this chapter
Cite this chapter
Miyasaka, M., Reynolds, J., Dudler, L., Beya, MF., Leiserson, W., Trnka, Z. (1985). Differentiation of B Lymphocytes in Sheep. II. Surface Phenotype of B Cells Leaving the ‘Bursa-Equivalent’ Lymphoid Tissue of Sheep, Ileal Peyer’s Patches. In: Klaus, G.G.B. (eds) Microenvironments in the Lymphoid System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2463-8_14
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2463-8_14
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9495-5
Online ISBN: 978-1-4613-2463-8
eBook Packages: Springer Book Archive