Evidence for the Existence of Two Distinct Types of Peyer’s Patches in Sheep

  • John Reynolds
  • Reinhard Pabst
  • Gerard Bordmann


Johann Peyer included a description of the Peyer’s patches (PP) in sheep as part of his monograph published in 1677 which provided the first detailed account of the “intestinal glands” that are found in all higher vertebrates. The inclusion of sheep in the list of species in which he noted PP was probably as a consequence of one of his other studies on the mechanisms of rumination. The PP in sheep have received attention periodically since that time. In 1928 Carlens published an account of the PP in domestic animals which included their distribution, ontogeny and age-related changes. We have recently reexamined these topics in the sheep and confirmed Carlens’ observations which showed that sheep PP have a number of important features (Reynolds and Morris, 1983).


Terminal Ileum Muscularis Mucosa Thymic Involution Proximal Ileum Dome Region 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • John Reynolds
    • 1
    • 3
  • Reinhard Pabst
    • 2
  • Gerard Bordmann
    • 3
  1. 1.Department of Medical PhysiologyUniversity of CalgaryCanada
  2. 2.Center of AnatomyMedical School of HannoverWest Germany
  3. 3.Basel Institute for ImmunologySwitzerland

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