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Effects of Lasers on Biologic Tissue: Options for Specificity

  • J. A. Parrish
Part of the Ettore Majorana International Science Series book series (EMISS, volume 22)

Abstract

In any tissue most biologic effects of optical radiation are usually caused by either or both of two basic mechanisms: (1) responses to photochemical reactions, and (2) responses to the heat caused by non-radiative deexcitation and dissipation of the absorbed energy. Host responses to extensive photochemical cell injury are not qualitatively very different from the inflammation and repair which occur from injury by many physical and chemical agents. However, in the case of more subtle cell alterations, the inherent specificity of photochemical reactions may lead to quantitative differences in host response to various wavelengths. In fact many biological responses to in vivo photochemical reactions can be very wavelength-dependant and quite specific. In vivo extracellular photochemical reactions may also have very specific effects on the host.

Keywords

Photochemical Reaction Thermal Alteration Spatial Confinement Inherent Specificity Normal Human Volunteer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    J. A. Parrish, T. B. Fitzpatrick, L. Tanenbaum, and M. A. Pathak, New Eng.J.Med., 291: 1207–1212 (1974).CrossRefGoogle Scholar
  2. 2.
    J. A. Parrish, R. S. Stern, and T. B. Fitzpatrick, “Dermatology Update: Reviews for Physicians,” S. Moschella, ed., Elsevier-North Holland Inc., New York, 313–338 (1982).Google Scholar
  3. 3.
    R. R. Anderson, K. F. Jaenicke, and J. A, Parrish, Mechanisms of selective vascular changes by dye lasers, in: “Lasers in Surgery and Medicine,” in press (1983).Google Scholar
  4. 4.
    R. W. Gange, K. D. Jaenicke, R. R. Anderson, and J. A. Parrish, Effect of pre-irradiation tissue target temperature upon selective vascular damage induced by 577 nm tunable dye laser pulses, in: “Microvascular Research,” in press (1983).Google Scholar
  5. 5.
    R. R. Anderson and J. A. Parrish, Selective photothermolysis: Precise microsurgery by selective absorption of pulsed radiation, Science, 220: 524–527 (1983).ADSCrossRefGoogle Scholar
  6. 6.
    J. A. Parrish, R. R. Anderson, T. Harrist, B. Paul, and G. F. Murphy, J. Invest. Dermatol., 80: 75S–80S (1983).CrossRefGoogle Scholar
  7. 7.
    R. R. Anderson and J. A. Parrish, Lasers in Surgery and Medicine, 1: 263–276 (1981).CrossRefGoogle Scholar
  8. 8.
    J. Greenwald, S. Rosen, R. R. Anderson, T. Harrist, F. MacFarland, J. Noe, and J. A. Parrish, J. Invest.Dermatol., 77:305–310 (1981).CrossRefGoogle Scholar
  9. 9.
    G. F. Murphy, R. S. Shephard, B. S. Paul, A. Menkes, R. R. Anderson, and J. A. Parrish, Organelle-specific injury to melanin-containing cells in human skin by pulsed laser irradiation, Lab. Invest., in press (1983).Google Scholar
  10. 10.
    B. S. Paul, R. R. Anderson, J. Jarve, and J. A. Parrish, The effect of temperature and other factors on selective microvascular damage caused by pulsed dye laser, J. Invest. Dermatol., in press (1973)Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • J. A. Parrish
    • 1
  1. 1.Department of Dermatology, Harvard Medical SchoolMassachusetts General HospitalBostonUSA

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