Testing Human lipoproteins for Mutagenic Activity in the Salmonella/Microsome Assay

  • J. Rueff
  • M. J. Halpern


In ancient Rome mean human lifespan was about 22 years whereas nowadays in USA it is about 74 years. Although this dramatic difference actually reflects a substantial improvement in general health care measures it also brought about a huge and increasing concern on the so-called “diseases of aging”, namely cardiovascular diseases and cancer as these two conditions represent the leading causes of death and disability in developed countries as well as the major challenges facing medical research.


Mutagenic Activity Lipoprotein Fraction Smooth Muscle Tumor General Health Care Human Lifespan 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • J. Rueff
    • 1
  • M. J. Halpern
    • 1
  1. 1.Dept. of Biochemistry and Centre for Lipid Research (INIC)Faculty of Medical Sciences UNLLisboaPortugal

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