Selected Aspects of Cell and Molecular Biology of In Vivo Biocompatibility

  • Roger E. Marchant
  • Kathleen M. Miller
  • Anne Hiltner
  • James M. Anderson

Abstract

The biocompatibility of an implanted material or prosthetic device is a dynamic and two-way process that involves the time dependent effects of the host on the material and the material on the host. The implantation of any synthetic material initiates a wound healing mechanism that is characterized by the inflammatory response. However, the inflammatory response itself involves complex and highly regulated interactions between specific cells and various molecular mediators. An understanding of these interactions which occur following biomaterial implantation has been hindered by the difficulty in quantifying the cellular and biological events.

Keywords

Migration Cage INFLAMMA TION Tuberculosis Polysaccharide 

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Roger E. Marchant
    • 1
  • Kathleen M. Miller
    • 1
  • Anne Hiltner
    • 1
  • James M. Anderson
    • 1
  1. 1.Departments of Pathology and Macromolecular ScienceCase Western Reserve UniversityClevelandUSA

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