Skip to main content

Electroencephalographic and Clinical Effects of Total Corpus Callosotomy

  • Chapter
Epilepsy and the Corpus Callosum

Abstract

Despite the availability of over 20 antiepileptic drugs (AEDs) and AED level monitoring, many patients continue to have seizures that are frequent and severe enough to cause physical injury. When the epileptic tissue can be demonstrated to be isolated to a surgically resectable part of the cortex lobectomy or topectomy can be performed, often with very gratifying results (Rasmussen, 1975). However, when the patient is found to have rapid secondary generalization from a surgically unapproachable lesion (because of size or location) or from multiple sites the surgical option has generally been excluded, even in cases of clear medical treatment failure

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Akelaitis, A. J., 1944, A study of gnosis, praxis and language following section of the corpus callosum and anterior commissure, J. Neurosurg. 1: 94–102.

    Article  Google Scholar 

  • Bogen, J. E., and Vogel, P. J., 1962, Cerebral commissurotomy in man, Bull. Los Angeles Neurol. Soc. 27: 169–172.

    Google Scholar 

  • Bogen, J. E., Fisher, E. D., and Vogel, P. J., 1965, Cerebral commissurotomy. A second case report, J. Am. Med. Assoc. 194: 1328–1329.

    Article  CAS  Google Scholar 

  • Huck, F. R., Radvany, J., Avila, J. O., Pires de Camargo, C. H., Marino, R., Jr., Ragazzo, P. C., Riva, D., and Arlant, P., 1980, Anterior callosotomy in epileptics with multiform seizures and bilateral synchronous spike and wave EEG pattern, Acta Neurochir. Suppl. 30: 127–135.

    CAS  Google Scholar 

  • Lombroso, C. T., and Erba, G., 1970, Primary and secondary bilateral synchrony in epilepsy, Arch. Neurol. 22: 321–334.

    PubMed  CAS  Google Scholar 

  • Luessenhop, A. J., de la Cruz, T. C., and Fenichel, G. M., 1970, Surgical disconnection of the cerebral hemispheres for intractable seizures. Results in infancy and childhood, J. Am. Med. Assoc. 213: 1630–1636.

    Article  CAS  Google Scholar 

  • Rasmussen, T., 1975, Cortical resection in the treatment of focal epilepsy, in: Advances in Neurology, Vol, 8, Neurosurgical Management of the Epilepsies ( D. P. Purpura, J. K. Penry, and R. D. Walter, eds.), Raven Press, New York, pp. 139–154.

    Google Scholar 

  • Rovit, R. L., Gloor, P., and Rasmussen, T., 1961, Intracarotoid amobarbital in epilepsy, Arch. Neurol. 5: 606–626.

    PubMed  CAS  Google Scholar 

  • Van Wagenen, W. P., and Herren, R. Y., 1940, Surgical division of commissural pathways in the corpus callosum. Relation to spread of an epileptic attack, Arch. Neurol. 44: 740–759.

    Google Scholar 

  • Wilson, D. H., Culver, C., Waddington, M., and Gazzaniga, M., 1975, Disconnection of the cerebral hemispheres. An alternative to hemispherectomy for the control of intractable seizures, Neurology 25: 1149–1153.

    PubMed  CAS  Google Scholar 

  • Wilson, D. H., Reeves, A., Gazzaniga, M., and Culver, C., 1977, Cerebral commissurotomy for control of intractable seizures, Neurology 27: 708–715.

    PubMed  CAS  Google Scholar 

  • Wilson, D. H., Reeves, A., and Gazzaniga, M., 1978, Division of the corpus callosum for uncontrollable epilepsy, Neurology 28: 649–653.

    PubMed  CAS  Google Scholar 

  • Wilson, D. H., Reeves, A., and Gazzaniga, M., 1982, “Central” commissurotomy for intractable generalized epilepsy: Series two, Neurology 32:687–697.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Plenum Press, New York

About this chapter

Cite this chapter

Gates, J.R., Maxwell, R., Leppik, I.E., Fiol, M., Gumnit, R.J. (1985). Electroencephalographic and Clinical Effects of Total Corpus Callosotomy. In: Reeves, A.G. (eds) Epilepsy and the Corpus Callosum. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2419-5_15

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2419-5_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9473-3

  • Online ISBN: 978-1-4613-2419-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics