Abstract
Our work on scoring the frequency of micronucleus (MNF) directly in 1–2 drops of human blood obtained from skin puncture was reported in a previous paper. The results of further study are given as follows:
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1.
MNF in 117 health donors (male 58, female 59) were in the range of 0–1%, with the mean of 0.14%, and about 20.5% of the samples with ≥ 0.5%.
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2.
The MNF in 100 workers dealing with radioactive materials was 0–8%, with a mean of 1.3%; the rate of detected positive was 69%, and 28% of them were ≥ 1%. The MNF in the exposed group differed significantly from the normal control.
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3.
Surveillance of workers exposed to technical PBNA (phenyl B-Naphthylamine), an antioxidant D incorporated into rubber, and a known animal carcinogen) was done and the result was positive.
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© 1984 Plenum Press, New York
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Xue, K.X. et al. (1984). Studies on Micronucleus Test by Human Skin Puncture. In: Chu, E.H.Y., Generoso, W.M. (eds) Mutation, Cancer, and Malformation. Environmental Science Research, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2399-0_40
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DOI: https://doi.org/10.1007/978-1-4613-2399-0_40
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