Summary
In 61 laboratories using a variety of prokaryotic and eukaryotic short-term assays a maximum of 42 chemicals were tested. The purpose of the study was to identify the best battery of assays for screening carcinogens. None of the assay systems correctly identified all the proven carcinogens or “noncarcinogens”. The individual assays were characterized by sensitivity (% of correct identification of carcinogens), specificity (% of correct identification of “noncarcinogens”), predictivity (% of carcinogens correctly identified among all the compounds tested) and hypersensitivity (% of compounds classified as carcinogens among all the compounds tested.
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© 1984 Plenum Press, New York
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Rédei, G.P., Acedo, G.N., Sandhu, S.S. (1984). Sensitivity, Specificity and Accuracy of the Arabidopsis Assay in the Identification of Carcinogens. In: Chu, E.H.Y., Generoso, W.M. (eds) Mutation, Cancer, and Malformation. Environmental Science Research, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2399-0_30
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DOI: https://doi.org/10.1007/978-1-4613-2399-0_30
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