The Use of Calcium Entry Blockers in Congestive Heart Failure

  • Robert Zelis
  • Edward Toggart

Abstract

Patients with severe congestive heart failure operate on a depressed ventricular function curve [28]. They experience symptoms and signs due to: (1) an inadequate cardiac output (especially with exercise) and/or (2) an increase in ventricular filling pressure. Low-output symptoms and signs result from redistribution of an inadequate cardiac output and include fatigue, pallor, and a decreased urinary output. Congestive symptoms and signs result from an increase in pulmonary and systemic venous pressure and fluid accumulation in tissues. The following may occur: shortness of breath from pulmonary congestion (pulmonary edema), edema in dependent portions of the body, hepatic enlargement and tenderness due to congestion, as well as ascites and pleural effusions.

Keywords

Fatigue Ischemia Angiotensin Cardiomyopathy Catecholamine 

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Robert Zelis
    • 1
  • Edward Toggart
    • 1
  1. 1.Cardiology Division, The Milton S. Hershey Medical CenterThe Pennsylvania State UniversityHersheyUSA

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