Skip to main content
SpringerLink
Log in
Book cover

Psychiatry the State of the Art pp 415–417Cite as

Lithium Discontinuation: Side-Effects, Withdrawl Symptoms, Rebound Effect

  • Chapter

  • 32 Accesses

Abstract

In an attempt to a) investigate to what extent side-effects attributed to lithium treatment are genuine b) see whether lithium discontinuation produces withdrawal symptoms c) observe the clinical course of the illness after lithium withdraw! and d) investigate the possibility of induction of a rebound phenomenon following lithium discontinuation, 18 patients suffering from recurrent affective disorders (14 women, 4 men, mean age 47.3±14.6, 17 bipolars and one with unipolar depression) were deprived of lithium treatment for 15 days (Christodoulou and Lykouras, 1982).

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References

  • Christodoulou, G.N., Siafakas, A., Rinieris, P.M., 1970, Side effects of lithium,Acta Psychiat. Belg., 77: 260.

    Google Scholar 

  • Christodoulou, G.N., Kokkevi, A., Lykouras, E.P., Stefanis, C.N., Papadimitriou, G.N., 1981, Effects of lithium on memory,Amer. J.Psychiat. 138: 847.

    PubMed  CAS  Google Scholar 

  • Christodoulou, G.N., Lykouras, E.P., 1982, Abrupt lithium discontinuation in manic-depressive patients,Acta Psychiat Scand, 65: 310.

    Article  PubMed  CAS  Google Scholar 

  • Lapierre, Y.D., Gagnon, A., Kokkinides, L., 1980, Rapid recurrence of mania following lithium withdrawal.,Biol. Psychiat., 15: 859.

    PubMed  CAS  Google Scholar 

  • Shopsin, B., Gershorv, S., 1973, Pharmacology-toxicology of the lithium ion. In: Gershon, S., Shopsin, B., 1973, “lithium. Its role in psychiatric research and treatment” Plenum Press. New York.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Psychiatry, Athens University, Medical School, Eginition Hospital, 74 Vassilissis Sofia Avenue, Athens, Greece

    George N. Christodoulou & Eleftherios P. Lykouras

Authors
  1. George N. Christodoulou
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Eleftherios P. Lykouras
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Académie de Paris, Université René Descartes, Paris, France

    P. Pichot

  2. University of Vienna, Vienna, Austria

    P. Berner , R. Wolf  & K. Thau ,  & 

Rights and permissions

Reprints and permissions

Copyright information

© 1985 Plenum Press, New York

About this chapter

Cite this chapter

Christodoulou, G.N., Lykouras, E.P. (1985). Lithium Discontinuation: Side-Effects, Withdrawl Symptoms, Rebound Effect. In: Pichot, P., Berner, P., Wolf, R., Thau, K. (eds) Psychiatry the State of the Art. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2363-1_65

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2363-1_65

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9446-7

  • Online ISBN: 978-1-4613-2363-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation