Cerebrospinal Fluid Amine Metabolites and Neuroendocrine Findings: Biochemical Markers in Suicide?

  • Csaba M. Banki
  • Mihály Arató
  • Zsuzsa Papp
  • Mihály Kurcz

Abstract

Some data indicate that suicidal behaviour in man may be associated with CNS biochemical alterations: the CSF concentration of 5HIAA has been found to be decreased in both suicidal1,2 and aggressive3 patients; MHPG was also correlated, although positively, with aggression4. In addition, dexamethasone nonsuppression occurred more frequently in suicidal patients5 and there was a significant correlation between CSF 5HIAA and postdexamethasone Cortisol.

Keywords

Depression Cortisol Schizophrenia Dexamethasone Tryptophan 

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Csaba M. Banki
    • 1
  • Mihály Arató
    • 2
  • Zsuzsa Papp
    • 3
  • Mihály Kurcz
    • 4
  1. 1.Regional Neuropsychiatric HospitalNagykáallóHungary
  2. 2.Hamilton Psychiatric HospitalCanada
  3. 3.National Institute for Nervous and Mental DiseasesBudapestHungary
  4. 4.Chinoin PharmaceuticalsBudapestHungary

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