Studies of the Effects of Pirlindole on Sleep

  • B. Ziegler
  • E. Schneider
  • S. Wegehaupt


Results of short-term studies indicate that antidepressant drugs produce a decrease in the amount of desynchronized sleep (REM-sleep) accompanied by an increase in REM-latency (a.o. Hartmann, 1968; Hartmann and Cravens, 1973; Schneider et al., 1975). It was of interest to examine the effects of the new antidepressant Pirlindole on recorded sleep and whether or not there is a rebound increase in REM-time after discontinuation of medication.


Antidepressant Drug Sleep Laboratory Sleep Complaint Recorded Sleep Statistical Significant Effect 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • B. Ziegler
    • 1
  • E. Schneider
    • 2
  • S. Wegehaupt
    • 3
  1. 1.Department of PsychiatryUniversity HomburgSaarGermany
  2. 2.Department of NeurologyUniversity FrankfurtMainGermany
  3. 3.Pharmaceutical Research Cassella FrankfurtMainGermany

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