Studies of the Effects of Pirlindole on Sleep
Results of short-term studies indicate that antidepressant drugs produce a decrease in the amount of desynchronized sleep (REM-sleep) accompanied by an increase in REM-latency (a.o. Hartmann, 1968; Hartmann and Cravens, 1973; Schneider et al., 1975). It was of interest to examine the effects of the new antidepressant Pirlindole on recorded sleep and whether or not there is a rebound increase in REM-time after discontinuation of medication.
KeywordsPlacebo Amitriptyline Sulpirid Pirlindole
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- Aitken, R.C.B ., 1969, Measurement of feeling using visual analogue scales, Proceedings Royal Soc. Med. 62:989.Google Scholar
- Rechtschaffen, A. and Kales, A. (eds.), 1968, A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects, Washington D.C.: Public Health Service, U.S. Goverment Printing Office.Google Scholar