Dilemmas Created by Prenatal Detection of Urinary Tract Anomalies

  • Warren E. Grupe
Part of the Developments in Nephrology book series (DINE, volume 17)


It has been slightly more than a decade since Garrett first reported the successful in-utero diagnosis of polycystic kidneys using ultrasound (1). Advances in ultrasonographic techniques has not only allowed a rapid improvement in the ability to study fetal anatomy, but has stimulated an equally rapid expansion of routine procedures, even when there is no special indication. As might be expected, the discovery of malformations has quickly expanded. The prevalence of abnormalities approximates 1–2 per thousand ultrasound procedures, of which 20–33% are anomalies of the genitourinary tract (2,3). Over 90% of the reported prenatally detected malformations have appeared in print since 1980 (4).


Amniotic Fluid Genitourinary Tract Pulmonary Hypoplasia Duodenal Atresia Ureteropelvic Junction Obstruction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Garret, W.J., Grunwald, G. and Robinson, D.E. Aust. New Zeal. Obstet. Gynaec. 10: 7–9, 1970.CrossRefGoogle Scholar
  2. 2.
    King, L.R. J. Urol 133: 155, 1985.Google Scholar
  3. 3.
    Gauderer, M.W.L., Jassani, M.N. and Izant, R.J. J. Ped. Surg. 29: 404–407, 1984.CrossRefGoogle Scholar
  4. 4.
    Broyer, M., Guest, G., Lestage, F. et al. Adv. in Nephrology 14: 21–38, 1985.Google Scholar
  5. 5.
    Kramer, S.A. J. Urol. 130: 641–646, 1983.PubMedGoogle Scholar
  6. 6.
    Diamond, D.A., Sanders, R., and Jeffs, R.D. J. Urol. 131: 1155–1159, 1984.PubMedGoogle Scholar
  7. 7.
    Bellinger, M.F., Comstock, C.H., Grosso, D. and Zaino, R. J. Urol. 129: 1238–1239, 1983.PubMedGoogle Scholar
  8. 8.
    Turnock, R.R. and Shawis, R. Arch. Dis. Child 59: 962–965, 1984.PubMedCrossRefGoogle Scholar
  9. 9.
    Editorial: When ultrasound shows fetal abnormality. Lancet 1: 618–619, 1985.Google Scholar
  10. 10.
    Mervyn Griffiths, D. and Gough, M.H. Lancet 1: 623–624, 1985.CrossRefGoogle Scholar
  11. 11.
    Sanders, R. and Graham, D. J. Ultrasound Med. 1: 341–348, 1982PubMedGoogle Scholar
  12. 12.
    Mahan, J., Gonzales, R., Godec, C.J. and Vernier, R.L.: Intrauterine obstructive uropathy: is early detection and intervention beneficial? Proceedings of the Northwestern Pediatric Society, 1982.Google Scholar
  13. 13.
    Hutson, J.M., McNay, M.B., MacKenzie, J.R. et al. Lancet 1: 621–623, 1985.PubMedCrossRefGoogle Scholar
  14. 14.
    Ruano-Gil, D., Coca-Payeras, A. and Tejedo-Mateu, A. Eur. Urol. 1: 287–293, 1975.PubMedGoogle Scholar
  15. 15.
    Wladimiroff, J.W. Brit. J. Obst. Gynaec. 82: 221–224, 1975.CrossRefGoogle Scholar
  16. 16.
    Waldimiroff, J.W. and Campbell, S. Lancet 1.: 151–154, 1974.CrossRefGoogle Scholar
  17. 17.
    Harrison, M.R., Filly, R.A., Parer, J.T., et al. JAMA 246: 635–639, 1981.PubMedCrossRefGoogle Scholar
  18. 18.
    Harrison, M.R., Golbus, M.S. and Filly, R.A. JAMA 246774–777, 1981.Google Scholar
  19. 19.
    Harrison, M.R., Golbus, M.S., Filly, R.A., et al. N. Eng. J. Med. 306: 591–593, 1982.CrossRefGoogle Scholar
  20. 20.
    Duckett, J.W., Harrison, M.R., de Lorimer, A.A., et al. Dialogues Pediat. Urol. 5: l–8, 1982.Google Scholar
  21. 21.
    Blane, C.E., Koff, S.A., Bowerman, R.A. and Barr, M., Jr. Radiology 247: 95–99, 1983.Google Scholar
  22. 22.
    Golbus, M.S., Harrison, M.R. and Filly, R.A. Sem. in Perinatology 7: 102–108, 1983.Google Scholar
  23. 23.
    Campbell, S. and Pearce, J.M. Clin. Obstet. Gynecol. 10: 475–506, 1983.Google Scholar
  24. 24.
    Beck, A.D. J. Urol. 105; 784–789. 1971Google Scholar
  25. 25.
    Bernstein, J. Ped. Clin. N. Amer. 18: 395–407, 1971.Google Scholar
  26. 26.
    Schwarz, R.D., Stephens, F.D. and Cussen, L. J. Invest. Urol. 19: 97–100, 1981.PubMedGoogle Scholar
  27. 27.
    Mackie, G.G. and Stephens, F.D. J. Urol. 114: 274–280, 1975.PubMedGoogle Scholar
  28. 28.
    Symchych, P.S. and Winchester, P. Amer. J. Path. 90: 779–782, 1978.Google Scholar
  29. 29.
    Harrison, M.R., Nakayama, D.K., Noall, R. and de Lorimier, A.A.: J. Pediatr. Surg. 17: 596–974, 1982.Google Scholar
  30. 30.
    Mauer, S., Dobrin, R. and Vernier, R. J. Pediatr. 84: 236–238, 1984.Google Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1987

Authors and Affiliations

  • Warren E. Grupe

There are no affiliations available

Personalised recommendations