Advertisement

Brain DNA Changes During Learning

  • S. Reinis
Part of the Topics in the Neurosciences book series (TNSC, volume 3)

Abstract

In this paper, evidence is considered which implicates neuronal DNA in the formation of a permanent memory trace. It is postulated that one of the early changes necessary for permanent morphological and biochemical adjustments of neurons, which are ultimately responsible for the formation of the memory trace, may concern the structure of DNA.

Keywords

Passive Avoidance Memory Trace Neuronal Nucleus Pyrimidine Derivative Label Thymidine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Koenig, H. J. Biophys. Biochem. Cytol 4: 785–792, 1958.PubMedCrossRefGoogle Scholar
  2. 2.
    Inoue, N., Suzuki, O. and Kato, T. O. Neurochem. 27: 113–119, 1976.CrossRefGoogle Scholar
  3. 3.
    Cameron, I.L., Pool, M.R.H. and Hoage, T.R. Cell Tissue Kinet. 12: 445–451, 1979.PubMedGoogle Scholar
  4. 4.
    Perrone Capano, C., D’Onofrio, G. and Giuditta, A. J. Neurochem. 38: 52–56, 1982.PubMedCrossRefGoogle Scholar
  5. 5.
    Kaplan, M.S. and Bell, D.H. Exp. Brain Res. 52: 1–5, 1983.PubMedCrossRefGoogle Scholar
  6. 6.
    Kimberlin, R.H., Shirt, D.B. and Colins, S.C. J. Neurochem. 23: 241–248, 1974.PubMedCrossRefGoogle Scholar
  7. 7.
    Kuenzle, C.C., Bregnard, A., Hubscher, V. and Ruch, F. Exp. Cell Res. 113: 151–160, 1978.PubMedCrossRefGoogle Scholar
  8. 8.
    Reinis, S. J. Biol. Psychol. 12: 45–48, 1970.Google Scholar
  9. 9.
    Reinis, S. Ghana Med. J. 9: 255–259, 1970.Google Scholar
  10. 10.
    Reinis, S. Psychopharmacologia 19: 34–39, 1971.PubMedCrossRefGoogle Scholar
  11. 11.
    Pietrzykowska, I. Mutation Res. 19: 1–11, 1973.PubMedGoogle Scholar
  12. 12.
    Smith, J.L. and Forbes, I.J. Austr. J. Exp. Biol. Med. Sci. 48: 267–274, 1970.CrossRefGoogle Scholar
  13. 13.
    Chalmers, A.H., Knight, P.R. and Atkinson, M.R. Austr. J. Exp. Biol. Med. Sci. 47: 263–270, 1969.CrossRefGoogle Scholar
  14. 14.
    Prusoff, W.H. Biochim. Biophys. Acta 39: 327–341, 1959.CrossRefGoogle Scholar
  15. 15.
    Aamodt, L. and Goz, B. Biochem. Pharmacol. 19: 2400–2403, 1970.PubMedCrossRefGoogle Scholar
  16. 16.
    Rizki, R.M. and Rizki, T.M. Experientia 28: 324–325, 1972.CrossRefGoogle Scholar
  17. 17.
    Commerford, S.L. and Joel, D.D. Biochem. Biophys. Res. Commun. 86: 112–118, 1979.PubMedCrossRefGoogle Scholar
  18. 18.
    Myers, D.K. and Feinendegen, L.E. Can. J. Physiol. Pharmacol. 53: 1014–1026, 1975.PubMedCrossRefGoogle Scholar
  19. 19.
    Reinis, S., Abbott, J. and Clarke, J.J. Physiol. Chem. Phys. 4: 440–448, 1972.PubMedGoogle Scholar
  20. 20.
    Hampton, E.G., Rich, M.A. and Eidenhoff, M.L. J. Biol. Chem. 235: 3562–3567, 1960.Google Scholar
  21. 21.
    Hofer, K.G. and Hughes, W.L. Radiåt. Res. 47: 94–109, 1971.PubMedCrossRefGoogle Scholar
  22. 22.
    Cooper, R.A., Perry, S. and Breitman, T.R. Cancer Res. 26: 2267–2272, 1966.PubMedGoogle Scholar
  23. 23.
    Reinis, S. and Lamble, R.W. Physiol. Chem. Phys. 4: 335–338, 1972.PubMedGoogle Scholar
  24. 24.
    Kirby, K.S. Biochem. J. 66: 495–504, 1957.PubMedGoogle Scholar
  25. 25.
    Lamble, R.W. Doctoral Dissertation, York University, Toronto, 1974.Google Scholar
  26. 26.
    Mori, K., Yamagami, S. and Kawakita, Y. J. Neurochem. 17: 835–843, 1970.PubMedCrossRefGoogle Scholar
  27. 27.
    Lowry, O.H., Rosebrough, N.H., Farr, A.L. and Randal, R.J. J. Biol. Chem. 193: 265–275, 1951.Google Scholar
  28. 28.
    Mejbaum, W. Zschr. Physiol. Chem. 258: 117–120, 1939.Google Scholar
  29. 29.
    Cleaver, J.E., Thomas, G.H. and Burki, H.J. Science 171: 996–998, 1972.CrossRefGoogle Scholar
  30. 30.
    Reinis, S. Physiol. Chem. Phys. 4: 391–397, 1972.PubMedGoogle Scholar
  31. 31.
    Dropp, J.J. and Sodetz, F.J. Brain Res. 33: 419–430, 1971.PubMedCrossRefGoogle Scholar
  32. 32.
    Uintzerith, M., Wittendorp, E., Rechenmann, R.V. and Mandel, P. J. Neurosci. Res. 3: 217–230, 1977.CrossRefGoogle Scholar
  33. 33.
    Vilenchik, M.M. and Tretjak, T.M. J. Neurochem. 29: 1159–1161, 1977.PubMedCrossRefGoogle Scholar
  34. 34.
    Salganik, R.I., Parvez, H., Tomsons, V.P. and Shumskaya, I.A. Neurosci. Lett. 36: 317–322, 1983.PubMedCrossRefGoogle Scholar
  35. 35.
    Montgomery, K.T., Biedler, O.L., Spengler, B.A. and Mélera, P.W. Proc. Natl. Acad. Sci. USA 80: 5724–5728, 1983.PubMedCrossRefGoogle Scholar
  36. 36.
    Giuditta, A., Abrescia, P. and Rutigliano, B. J. Neurochem. 31: 983–987, 1978.PubMedCrossRefGoogle Scholar
  37. 37.
    Reinis, S. and Goldman, J.M. The Chemistry of Behavior. Plenum Press, New York, 1982.Google Scholar
  38. 38.
    Hebb, D.O. The Organization of Behavior: A Neurophysiological Theory. J. Wiley & Sons, New York, 1949.Google Scholar

Copyright information

© Martinus Nijhoff Publishing 1986

Authors and Affiliations

  • S. Reinis
    • 1
  1. 1.Department of PsychologyUniversity of WaterlooOntarioCanada

Personalised recommendations