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Neuroregulation of Autonomic, Endocrine and Immune Systems pp 151–182Cite as

Opioids and Other Neuropeptides: Functional Interactions with Autonomic Systems

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Part of the book series: Topics in the Neurosciences ((TNSC,volume 2))

Abstract

The autonomic nervous system functions at a delicate balance to sustain a relatively constant internal milieu despite exposure to ever changing external and internal environments. For example, changes in temperature and altitude evoke compensatory autonomic responses to maintain body temperature and respiratory function. Likewise, sudden standing can lower arterial pressure, resulting in activation of baroreceptor reflex arcs to sustain cardiovascular function. In addition to alterations in the external environment, disease and injury can necessitate compensatory autonomic responses. However, in pathophysiological states, the autonomic nervous system may be severely compromised and unable to function in the rapid restoration of homeostasis.

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Authors and Affiliations

  1. Neuropharmacology Branch, Department of Medical Neurosciences, Division of Neuropsychiatry, Walter Reed Army Institute of Research, Washington, DC, 20307-5100, USA

    John W. Holaday

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Editors and Affiliations

  1. Monsanto Company, St. Louis, Missouri, USA

    Robert C. A. Frederickson Ph.D. (Senior Director) (Senior Director)

  2. Central Nervous System Research Searle Research and Development, G. D. Searle & Co., Skokie, Illinois, USA

    Robert C. A. Frederickson Ph.D. (Senior Director) (Senior Director)

  3. Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA, 46223

    Hugh C. Hendrie M. B. Ch.B. (Chairman and Albert E. Sterne Professor of Psychiatry) (Chairman and Albert E. Sterne Professor of Psychiatry)

  4. Section of Applied and Theoretical Neurobiology The Institute of Psychiatric Research and Departments of Psychiatry and Biochemistry, Indiana University School of Medicine Indiana University Medical Center, Indianapolis, Indiana, USA, 46223

    Joseph N. Hingtgen Ph.D. (Professor of Psychology and Neurobiology) (Professor of Psychology and Neurobiology)

  5. Departments of Pharmacology & Toxicology & Psgchiatry Program in Medical Neurobiologg, Indiana University School of Medicine, Indianapolis, Indiana, USA, 46223

    Morris H. Aprison Ph.D. (Distinguished Professor of Neurobiology and Biochemistry) (Distinguished Professor of Neurobiology and Biochemistry)

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Holaday, J.W. (1986). Opioids and Other Neuropeptides: Functional Interactions with Autonomic Systems. In: Frederickson, R.C.A., Hendrie, H.C., Hingtgen, J.N., Aprison, M.H. (eds) Neuroregulation of Autonomic, Endocrine and Immune Systems. Topics in the Neurosciences, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2315-0_8

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