Skip to main content
SpringerLink
Log in

The Predilution Mode for Continuous Arteriovenous Hemofil Tration

  • Chapter
Acute Continuous Renal Replacement Therapy

Part of the book series: Developments in Nephrology ((DINE,volume 13))

Abstract

We have been using the predilution mode as the exclusive method of fluid replacement during CAVH. Our experience with this technique has shown an enhanced filtrate output and a net increase in urea clearance when compared to the postdilution mode. This chapter will offer a brief outline of the background and theory related to predilution and a detailed description of its use in clinical practice.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Kaplan AA, Longnecker RE, Folkert VW: Suction-assisted continuous arteriovenous hemofiltration. Trans Am Soc Artif Intern Organs 29:408–412, 1983.

    PubMed  CAS  Google Scholar 

  2. Kramer P: Discussion, ibid, p 413.

    Google Scholar 

  3. Kramer P, Kaufhold G, Grone HJ, et al: Management of anuric intensive-care patients with arteriovenous hemofiltration. Int J Artif Organs 3:225–230, 1980.

    PubMed  CAS  Google Scholar 

  4. Henderson LW: Hemofiltration. Kidney Int 13 Supple: S145–S149, 1978.

    Google Scholar 

  5. Henderson LW: Pre vs. post dilution hemofiltration. Clin Nephrol11:120–124, 1979.

    PubMed  CAS  Google Scholar 

  6. Paganini EP, Flaque J, Whiteman G, Nakamoto S: Amino acid balance in patients with oliguric acute renal failure undergoing slow continuous ultrafiltration (SCUF). Trans Am Soc Artif Intern Organs 28:615–620, 1982.

    PubMed  CAS  Google Scholar 

  7. Lauer A, Saccaggi A, Ronco C, et al: Continuous arteriovenous hemofiltration in the critically ill patient. Ann Intern Med 99:455–460, 1983.

    PubMed  CAS  Google Scholar 

  8. Kaplan AA, Longnecker RE, Folkert VW: Continuous arteriovenous hemofiltration: a report of six months’ experience. Ann Intern Med 100:358–367, 1984.

    PubMed  CAS  Google Scholar 

  9. Geronemus R, Von Albertini B, Glabman S, et al: Enhanced small molecular clearances in hemofiltration. Proc Clin Dial Transplant Forum 8:147–151, 1978.

    PubMed  CAS  Google Scholar 

  10. Landis E, Pappenheimer JR: Circulation. In: Handbook of Physiology, Sec 2, Vol II, Hamilton WF, Dow P (eds), American Physiological Society, Washington, D.C., 2:972–974.

    Google Scholar 

  11. Kaplan AA: Predilution versus postdilution for continuous arterio-venous hemofiltration. Trans Am Soc Artif Intern Organs 31: In Press.

    Google Scholar 

  12. Katz MA, Hull AR: Transcellular creatinine disequilibrium and its significance in hemodialysis. Nephron 12:171–177, 1974.

    Article  PubMed  Google Scholar 

  13. Nolph KD, Bass OE, Maher JF: Acute effects of hemodialysis on removal of intracellular solutes. Trans Am Soc Artif Intern Organs 20:622–627, 1974.

    PubMed  Google Scholar 

  14. Cheung AK, Alford MF, Wilson MW, et al: Urea movement across erythrocyte membrane during artificial kidney treatment. Kidney Int 23:866–869, 1983.

    Article  PubMed  CAS  Google Scholar 

  15. Kaplan AA: The predilution mode for continuous arteriovenous hemofiltration (CAVH) (abstract). Presented at the Scientific Symposium of the American Israeli Nephrology Association, September 8-10, Tel-Aviv.

    Google Scholar 

  16. Kaplan AA: The effect of predilution during continuous arterio-venous hemofiltration (abstract). Presented at the 17th Annual Meeting of the American Society of Nephrology, December 9-12, Washington, D.C., p 66A.

    Google Scholar 

  17. Kaplan AA: Procedure manual: Continuous arterio-venous hemofiltration. Clinical protocol from the John Dempsey Hospital, university of Connecticut Health Center, Farmington, CT (copies available from the author).

    Google Scholar 

  18. Colton CK, Henderson LW, Ford CA, Lysaght MJ: Kinetics of hemodiafiltration: I. In vitro transport characteristics of a hollow-fiber blood ultrafilter. J Lab Clin Med 85:355–371, 1971, 1975.

    PubMed  CAS  Google Scholar 

  19. Henderson LW, Colton CK, Ford CA: Kinetics of hemodiafiltration: II. Clinical characterization of a new blood cleansing modality. J Lab Clin Med 85:372–391, 1975.

    PubMed  CAS  Google Scholar 

  20. Bennett WM, Muther RS, Parker RA, et al: Drug therapy in renal failure: dosing guidelines for adults: Part I. Antimicrobial agents, analgesics. Ann Intern MEd 93: (1 pt 1)62–89, 1980.

    PubMed  CAS  Google Scholar 

  21. Bennett WM, Muther RS, Parker RA, et al: Drug therapy in renal failure: dosing guidelines for adults: Part II. Sedatives, hypnotics, and tranquilizers; cardiovascular, antihypertensive and diuretic agents; miscellaneous agents. Ann Intern Med 93:286–325, 1980.

    PubMed  CAS  Google Scholar 

  22. Kaplan AA, Longnecker RE, Folkert VW: Continuous hemofiltration. Letters to the Editor. Ann Intern Med 101:145–146, 1984.

    Google Scholar 

  23. Golper TA, Pulliam J, Bennett WM: Removal of therapeutic drugs by continuous arteriovenous hemofiltration. Arch Intern Med 145:1651–1652, 1985.

    Article  PubMed  CAS  Google Scholar 

  24. Golper TA, Wedel SK, Kaplan AA, et al: Drug removal during continuous arteriovenous hemofiltration: theory and clinical observations. Int J Artif Intern Organs (in press).

    Google Scholar 

  25. Golper TA, Saad AM: Gentamicin and phenytoin in vitro sieving characteristics through hollow-fiber polysulfone hemofilters. Submitted for publication.

    Google Scholar 

  26. Henderson LW, Silverstein ME, Ford CA, Lysaght MJ: Clinical response to maintenance hemodiafiltration. Kidney Int 7 Supple 2:S58–S63, 1975.

    Google Scholar 

  27. Man NK, Funck-Brentano JL: Hemofiltration, an alternative method for treatment of end-stage renal failure. In: Hamburger J (ed), Advances in Nephrology, Vol. VII, Chicago: Yearbook Medical Publishers, pp 293–310, 1978

    Google Scholar 

  28. Kaplan AA, Toueg S, Merrow M, Kennedy TL: First clinical trials of anew polysulphone membrane for use with continuous arteriovenous hemofiltration (abstract). Presented at the Third Annual Meeting of the International Society of Hemofiltration, October 9–10, New York, NY, 1985.

    Google Scholar 

  29. Kaplan AA, Toueg S, Merrow M, Kennedy TL: Biocompatibility and efficiency of a new polysulphone membrane for use with continuous arteriovenous hemofiltration. To be presented at the VI Annual Symposium of Hemoperfusion and Blood Detoxification, September 29—October 2, 1985, Mexico City, Mexico.

    Google Scholar 

  30. Kaplan AA, Toueg S., Merrow M, Kennedy TL: Complement kinetics during continuous arteriovenous hemofiltration: studies with a new polysulphone membrane (abstract). Am Soc Nephrol, 1985.

    Google Scholar 

  31. Leypoldt JK, Frigon RP, Henderson LW: Dextran sieving coefficients of hemofiltration membranes. Trans Am Soc Artif Intern Organs 29:678–683, 1983.

    PubMed  CAS  Google Scholar 

  32. Eisele G, Paganini EP: Heparin-free continuous acute renal replacement therapy (abstract). Am Soc Artif Intern Organs 14:46, 1985.

    Google Scholar 

  33. Kaplan AA: Continuous arteriovenous hemofiltration (CAVH): an alternative to dialysis in the intensive care setting. VA Practitioner 1:34–38, 1984.

    Google Scholar 

  34. Williams HE: Oxalic acid and the hyperoxaluric syndromes. Kidney Int 13:410–417, 1978.

    Article  PubMed  CAS  Google Scholar 

  35. Jacobsen E, Mosbaek N: Primary hyperoxaluria treated with haemodialysis and kidney transplantation. Dan Med Bull 21:72–76, 1974.

    PubMed  CAS  Google Scholar 

  36. Rosier JGMC, Baadenhuijsen H, Koene RAP: Long-term survival of a renal allograft in a patient with primary hyperoxaluria (type I). Neth J Med 24:179–184, 1981.

    PubMed  Google Scholar 

  37. Kaplan AA, Longnecker RE, Folkert VW: Continuous hemofiltration. Letters to the Editor. Ann Intern Med 101:146–147, 1984.

    Google Scholar 

  38. Kramer P, Bohler J, Kehr A, et al: Intensive care potential of continuous arteriovenous hemofiltration. Am Soc Artif Intern Organs 28:28–32, 1982.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. University of Connecticut School of Medicine, Farmington, Connecticut, USA

    A. Kaplan

Authors
  1. A. Kaplan
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Hypertension and Nephrology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA

    Emil P. Paganini M.D., F.A.C.P. (Head, Section of Dialysis and Extracorporeal Therapy) (Head, Section of Dialysis and Extracorporeal Therapy)

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Martinus Nijhoff Publishing

About this chapter

Cite this chapter

Kaplan, A. (1986). The Predilution Mode for Continuous Arteriovenous Hemofil Tration. In: Paganini, E.P. (eds) Acute Continuous Renal Replacement Therapy. Developments in Nephrology, vol 13. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2311-2_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2311-2_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9422-1

  • Online ISBN: 978-1-4613-2311-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation