Abstract
Hemofiltration has been used in the past mainly for the treatment of renal failure (12,14). Recently, application of hemofiltration other than for renal failure, such as cardiac failure, septic shock, and intoxications has been evaluated (3–5). The main mode of action is the dehydration along with the elimination of toxic substances. It has been proved, that especially during extracorporeal circulation (ECC) and various shock states, humoral toxic substances are released to the circulation. These substances cause a negative inptropic effect on the heart and have also been claimed to contribute to pulmonary dysfunction and peripheral vasoparalysis (5,20). I will discuss hemofiltration in relation to this pathophysiological mechanism, during cardiac surgery (both during and after ECC), in cardiomyopathy, and in sepsis with acute respiratory failure.
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© 1986 Martinus Nijhoff Publishing
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Wolner, E. (1986). Continuous Arteriovenous Hemofiltration —Applications other than for Renal Failure. In: Paganini, E.P. (eds) Acute Continuous Renal Replacement Therapy. Developments in Nephrology, vol 13. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2311-2_16
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DOI: https://doi.org/10.1007/978-1-4613-2311-2_16
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