An autoradiographic approach for studying the distribution of neurotransmitter receptor binding sites on biopsy samples of human gliomas
A technique for the autoradiographic localisation of neurotransmitter binding sites on human gliomas in biopsy samples is described. Using this approach it is possible to correlate the distribution of neurotransmit-ter binding sites with histological findings on the same tissue section. The distribution of nicotinamide adenine dinucleotide, cholinergic muscarinic and noradrenergic β-receptors in astrocytoma biopsy samples are reported and their distribution compared with the histological appearance of the biopsy section.
Key wordshuman gliomas autoradiography receptors neurotransmitters
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