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Prognostic Factors in Small Cell Lung Cancer: An Analysis of 874 Consecutive Patients

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Book cover Lung Cancer: Basic and Clinical Aspects

Part of the book series: Cancer Treatment and Research ((CTAR,volume 28))

Abstract

The introduction of combination chemotherapy for the treatment of small cell lung cancer (SCC) has resulted in substantial improvements in overall survival duration and in the chances of being alive and disease-free two to three years from diagnosis. Current trials in patients aged ≤70–75 provide average values for median survival duration and two years disease-free survival of about 14–16 months and 10–20%, respectively, for patients with limited stage disease. The corresponding figures for extensive stage disease are around 8–11 months and 1–2% [1]. The prognostic differences between patients at opposite ends of the disease spectrum are thus considerable. Although variation in prognosis is less within each of the two disease stages it is great enough to produce both false positive and false negative interpretations of results from therapeutic trials. Prognostic factors i.e. variables with a well established relationship to the prognosis serve as indicators of this uncontrollable variation.

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Authors
  1. Kell Østerlind
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Editors and Affiliations

  1. Department of Oncology II, Finsen Institute, 49 Strandsoulevarden, DK - 2100, Copenhagen, Denmark

    Heine H. Hansen

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© 1986 Martinus Nijhoff Publishers, Boston

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Østerlind, K. (1986). Prognostic Factors in Small Cell Lung Cancer: An Analysis of 874 Consecutive Patients. In: Hansen, H.H. (eds) Lung Cancer: Basic and Clinical Aspects. Cancer Treatment and Research, vol 28. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2295-5_8

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  • DOI: https://doi.org/10.1007/978-1-4613-2295-5_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9414-6

  • Online ISBN: 978-1-4613-2295-5

  • eBook Packages: Springer Book Archive

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