Abstract
Titin (also called connectin) represents a pair of closely related, highly elusive megadalton polypeptides, which together are among the most abundant myofibrillar proteins in skeletal and heart muscles from a wide range of vertebrates and invertebrates (Wang, 1985). It is suggested that titin constitutes a major component of an elastic, endosarcomeric, superthin filament lattice that coexists with myosin and act in filaments and serves as an organizing template or dynamic scaffold (Wang, 1984).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Gassner, D ., 1985, Myofibrillar interaction of blot immunoaffinity purified antibodies against native titin as studied by direct immunofluorescence and immunogold staining, Eur. J. Cell. Biol., submitted.
Gassner, D., Shraideh, Z., and Wohlfarth-Bottermann, K.-E., 1983, An extraction resistant tensile protein in the protoplasmic matrix of Physarum, Cell Biol. Int. Rep ., 7: 905.
Gassner, D., Shraideh, Z., and Wohlfarth-Bottermann, K.-E., 1985, A giant titin-like protein in Physarum polycephalum: evidence for its candidacy as a major component of an elastic cytoskeletal superthin filament lattice, Eur. J. Cell Biol ., 37: 44.
Maruyama,. K., Kimura, S., Yoshidomi, H., Sawada, H., and Kikuchi, M., 1984, Molecular size and shape of β-connectin, an elastic protein of striated muscle, J. Biochem ., 95: 1423.
Maruyama, K., Matsubara, S., Natore, R., Nonomura, Y., Kimura, S., Ohashi, K., Murokami, F., Handa, S., and Eguchi, G., 1977, Connectin, an elastic protein of muscle. Characterization and function, J. Biochem ., 82: 317.
Ozaki, K., and Maruyama, K., 1980, A connectin-like protein from the Plasmodium Physarum polycephalum, J. Biochem ., 88: 883.
Trinick, J. A., Knight, P., and Whiting, A., 1984, Purification and properties of native titin, J. Mol. Biol ., 180: 331.
Wang, K., 1982, Purification of titin and nebulin, Methods Enzymol ., 85: 264.
Wang, K., 1984, Cytoskeletal matrix in striated muscle. The role of titin, nebulin and intermediate filaments, in: “Contractile Mechanisms in Muscle”, G. H. Pollack and H. Sugi, eds., p. 285, Plenum Press, New York.
Wang, K., 1985, Sarcomere-associated cytoskeletal lattices in stri-ated muscle. Review and hypothesis, in: “Cell and Muscle Motility”, J. W. Shay, ed., p. 315, Plenum Press, New York.
Wang, K., Ramirez-Mitchell, R., and Palter, D., 1984, Titin is an extraordinarily long, flexible, and slender myofibrillar protein, Proc. Natl. Acad. Sci., U.S.A ., 81: 3685.
Wohlfarth-Bottermann, K. E., 1983, Dynamic cellular phenomena in Physarum accessible to laser techniques, in: “The Application of Laser Light Scattering to the Study of Biological Motion”, J. C. Earnshaw and M. W. Steer, eds., NATO ASI Series, Series A: Life Sciences, Vol. 59, p. 501, Plenum Press, New York and London.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Plenum Press, New York
About this chapter
Cite this chapter
Gassner, D. (1986). A Titin-Like Protein is Present in Physarum polycephalum — Present Knowledge. In: Dove, W.F., Dee, J., Hatano, S., Haugli, F.B., Wohlfarth-Bottermann, KE. (eds) The Molecular Biology of Physarum polycephalum . NATO ASI Series, vol 106. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2203-0_15
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2203-0_15
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9294-4
Online ISBN: 978-1-4613-2203-0
eBook Packages: Springer Book Archive