Skip to main content

Synergistic Anti-Tumor Effect of an Immunopotentiator (PAV) and an Inhibitor (Cimetidine) of T-Suppressor Cells

  • Chapter
Book cover Viruses, Immunity, and Immunodeficiency

Abstract

As our understanding of the complex polyantigenic nature of the human cancer cell expands, it becomes more apparent that it would require the development of a large catalogue of specific vaccines, a large library to fill them, or a battery of monoclonal antibodies for the many types of known and undiscovered human cancer.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. J. I. Colon, A. M. Marchand, A. A. Roman, and E. A. Santiago-Delpín, The immunotherapeutic effect of a polyantigenic vaccine in animal tumor models, Bol. Asoc. Med. PR 73: 162 (1981).

    CAS  Google Scholar 

  2. J. I. Colón, A. M. Marchand, M. T. Rodríguez, and D. Valldejuli, Stimulation of phytohemagglutinin blast transformation in cancer patients by a polyantigenic vaccine, in: “Regulation of the Immune Response,” P. L. Ogra and D. M. Jacobs, eds., (1982).

    Google Scholar 

  3. R. R. M. Gifford, S. M. Hatfield, and J. R. Schmidtke, Cimetidine induced augmentation of human lymphocyte blastogenesis by mitogen, bacterial antigen and alloantigen, Transplantation 29: 143 (1980).

    Article  PubMed  CAS  Google Scholar 

  4. R. R. M. Gifford, R. M. Ferguson, and B. V. Voss, Cimetidine reduction of tumor formation in mice, Lancet i: 638 (1981).

    Google Scholar 

  5. S. Borgstrom, F. E. von Eyben, P. Flodgren, B. Axelsson, and H. Sjogren, Human leucocyte interferon and cimetidine for metastatic melanoma, N. Eng. J. Med. 307: 1080 (1982).

    CAS  Google Scholar 

  6. J. L. Webb, “Enzymes and Metabolic Inhibitors,” Academic Press, New York (1963).

    Google Scholar 

  7. E. Ríos-Olivares, A. M. Orraca, A. M. Marchand, and J. I. Colón, Cell growth inhibiting factor induced by a polyantigenic vaccine, Abstract of ASM 88 (1981).

    Google Scholar 

  8. Z. M. Orraca, E. Ríos-Olivares, A. M. Marchand, and J. I. Colón, Inhibition of DNA synthesis in L-929 cells by spleen homogenates of mouse injected with a polyantigenic vaccine, in press.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Plenum Press, New York

About this chapter

Cite this chapter

Rios-Olivares, E., Orraca, Z.M., Colon, J.I. (1986). Synergistic Anti-Tumor Effect of an Immunopotentiator (PAV) and an Inhibitor (Cimetidine) of T-Suppressor Cells. In: Szentivanyi, A., Friedman, H. (eds) Viruses, Immunity, and Immunodeficiency. University of South Florida International Biomedical Symposia Series. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2185-9_33

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2185-9_33

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9286-9

  • Online ISBN: 978-1-4613-2185-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics