Dexamethasone suppression test in senile dementia of the Alzheimer type
The dexamethasone suppression test (DST) has been widely studied in depressive patients. According to Carroll (1), the average sensitivity of this test is 45% among depressed patients irrespective of the etiology of the depression. Little is known about DST results in dementia of the Alzheimer type (SDAT) and in non demented elderly patients and there are conflicting results in the literature (2–6). The purpose of the present investigation was to determine the frequency of abnormal DST responses in a population of elderly inpatients affected with SDAT compared to a group of control mentally healthy patients of similar age range.
KeywordsDepression Dementia Cortisol Dexamethasone Norepinephrine
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