Down’s Syndrome and Alzheimer’s Disease: Are Common Genes From Human Chromosome 21 Involved In Both Disorders?

  • Y. Groner
  • N. Dafni
  • L. Sherman
  • D. Levanon
  • Y. Bernstein
  • E. Danciger
  • O. Elroy-Stein
  • A. Neer
Part of the Advances in Behavioral Biology book series (ABBI, volume 29)

Abstract

Why do most victims of Down’s syndrome (D.S.) develop Alzheimer’s dementia (A.D.) in middle age? The intriguing links between D.S, an inborn chromosomal disorder, and A.D, a condition that develops late in life in individuals with no obvious genetic abnormality were recognized many years ago. Nevertheless, the actual metabolic faults underlying both these conditions are still unknown (1–3).

Keywords

Superoxide Interferon Prostaglandin Neurol Fructose 

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Y. Groner
    • 1
  • N. Dafni
    • 1
  • L. Sherman
    • 1
  • D. Levanon
    • 1
  • Y. Bernstein
    • 1
  • E. Danciger
    • 1
  • O. Elroy-Stein
    • 1
  • A. Neer
    • 1
  1. 1.Department of VirologyThe Weizmann Institute of ScienceRehovotIsrael

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