Abstract
Catecholamines (CA) and indolamines (IA) can be visualized in histochemical preparations by the use of the formaldehyde induced fluorescence (FIF) method (Falck and Hillarp, 1962). In addition to morphological information on the localization, size and shape of monoaminergic neurones, this method can also provide information on the local concentration of CA and IA.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Benno, R.H., Tucker, L.W., Joh, T.H. and Reis, D.J. (1982). Quantitative immunocytochemistry of tyrosine hydroxylase in rat brain. Brain Res. 246, 225–236.
Bugnon, C., Fellman, D., Gauget, A. and Cardor, J. (1982). Ontogeny of corticoliberin neuroglandular system in rat brain. Nature (Lond.) 298, 159–161.
Descarries, L., Beaudet, A. and Watkins, K.C. (1975). Sertotonin nerve terminals in adult rat neocortex. Brain Res. 100, 563–588.
Ehinger, B., Falck, B. and Sporrong, B. (1970). Possible axo-axonal synapses between peripheral adrenergic and cholinergic nerve terminals. Z. Zellforsch. 107, 308–321.
Einarsson, P., Hallmann, H. and Jonsson, G. (1975). Quantitative microfluorimetry of formaldehyde induced fluorescence of dopamine in the caudate nucleus. Med. Biol. 53, 15–24.
Enerbäck, L. and Jarlstedt J. (1975). A cytofluorimetric and radiochemical analysis of the uptake and turnover of 5-hydroxy-tryptamine in mast cells. J. Histochern. 23, 128–135.
Falck, B., Hillarp, N.A., Thieme, G. and Torp, A. (1962). Fluorescence of catecholamines and related compounds condensed with formaldehyde. J. Histochern. Cytochem. 10, 348–354.
Fuxe, K., Fredholm, B.B., Agnati, L.F. and Corrodi, H. (1978). Dopamine receptors and ergot drugs. Evidence that an engolene derivative is a differential agonist at subcortical limbic dopamine receptors. Brain Res. 46, 295–311.
Katzman, R., Broida, R. and Raine, C.S. (1977). Reinnervation, myelination and organization of iris tissue implanted into the rat midbrain-an ultrastructural study. Brain Res. 138, 423–433.
Lichtensteiger, W. (1970). Katecholaminhaltige Neurone in der neuroendokrinen Steuerung. Prog. Histochem. Cytochem. 1 185–276.
Löfström, A., Jonsson, G., Wiesel, F. A. and Fuxe, K. (1976). Microfluorimetric quantitation of cathecholamine fluorescence in rat median eminence II turnover changes in hormonal states. J. Histochem. Cytochem. 24, 430–442.
Schipper, J. and Tilders, F.J.H. (1979a). On the presence of extraneuronal catecholamine in the iris of the rat: a scanning microfluorimetric study. Neurosci. Lett. 12 229–234.
Schipper, J. and Tilders, F.J.H. (1982). Quantification of formaldehyde induced fluorescence and its application in neurobiology. Brain Res. Bull. 9 69–80.
Schipper, J. and Tilders, F.J.H. (1983). A new technique for studying specificity of immunocytochemical procedures; specificity of serotonin immunostaining. J. Histochem. Cytochem. 31, 12–18.
Schipper, J., Tilders, F.J.H., Groot Wassink, R., Boleij, H.F. and Ploem, J.S. (1980a). Microfluorimetric scanning of sympathetic nerve fibres: quantitation of extraneuronal and neuronal fluorescence with aid of histogram analysis. J. Histochem. Cytochem. 28, 124–132.
Schipper, J., Tilders, F.J.H. and Mulder, A.H. (1980b). Extraneuronal catecholamine in the iris of the rat: a consequence of nonsynaptic neurotransmission? Neuroscience 5, 745–751.
Schipper, J., Tilders, F.J.H. and Ploem, J.S. (1978). Microfluorimetric scanning of sympathetic nerve fibres: an improved method to quantitate biogenic amines. J. Histochem. Cytochem. 26, 1055–1066.
Schipper, J., Tilders, F.J.H. and Ploem, J.S. (1979b). Extraneuronal catecholamine as an index for sympathetic activity: A scanning microfluorimetric study on the iris of the rat. J. Pharmacol. Exp. Ther. 211, 265–270.
Schipper, J., Tilders, F.J.H. and Ploem, J.S. (1980c). A scanning microfluorimetric study on sympathetic nerve fibres: intra-neuronal differences in noradrenaline turnover. Brain Res. 190, 459–471.
Schipper, J., Werkman, T.R. and Tilders, F.J.H. (1984). Quantitative immunocytochemistry of corticotropin Releasing Factor. Studies on nonbiological models and on hypothalamic tissues of rats after hypophysectomy, adrenalectomy and dexamethasone treatment. Brain Res. 293, 111–118.
Smelik, P.G ., (1977). Some aspects of corticosteroid feedback actions. Ann. N.Y. Acad. Sci297 , 580–590.
Sternberger, L.A. and Petrali, J.P. (1975). Quantitative immunocytochemistry of pituitary receptors for luteinizing hormone- releasing hormone. Cell Tiss. Res. 162, 141–146.
Tilders, F.J.H., Ploem, J.S. and Smelik, P.G. (1974). Quantitative microfluorimetric studies on formaldehyde induced fluorescence of 5-hydroxytryptamine in the pineal gland of the rat. J. Histochem. Cytochem. 22, 967–975.
Tilders, F.J.H., Schipper, J., Lowry, P.J. and Vermes, I. (1982). Effects of hypothalamus lesions on the presence of CRF immunoreactive nerve terminals in the median eminence and on the pituitary-adrenal response to stress. Regulatory Peptides 5, 77–84.
Vale, W., Spiess, J., Rivier, C. and Rivier, J. (1981). Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and ß-endorphin. Science 213, 1394–1397.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 The Wenner-Gren Centre
About this chapter
Cite this chapter
Schipper, J. (1985). Quantitative Cytochemical Studies on Catecholaminergic and Peptidergic Nerve Terminals. In: Agnati, L.F., Fuxe, K. (eds) Quantitative Neuroanatomy in Transmitter Research. Wenner-Gren Center International Symposium Series, vol 42. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2139-2_19
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2139-2_19
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9263-0
Online ISBN: 978-1-4613-2139-2
eBook Packages: Springer Book Archive