Abstract
The analysis of bioelectric phenomena requires knowledge of the thermodynamics and kinetics of electric field effects on chemical reactions. Chemical relaxation kinetics in high electric fields is the method of choice in order to imitate the high electric fields operative in living entities like membranes or close to fixed charges like those in proteins and nucleic acids. The present account covers elementary aspects of chemical electric field effects. Part I deals with the thermodynamic foundations of the analytical formalism required for a rigorous treatment of chemical field effects. Part II utilizes this frame of concepts and provides kinetic information as to how to investigate chemical and orientational contributions to structural changes in macromolecules and membrane organizations. The basic formalism established so far for isolated macromolecular systems may be extended to treat more complex bioelectric phenomena on the level of membranes and of cells.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
K. S. Cole, Membranes, Ions and Impulses, University of California Press (1968).
I. Tasaki, Physiology and Electrochemistry of Nerve Fibers, Academic, New York (1982).
D. Nachmansohn and E. Neumann, Chemical and Molecular Basis of Nerve Activity, Rev., Academic, New York (1975).
P. I. Dorogi and E. Neumann, Proc. Natl. Sci. USA 77, 6582–6586 (1980).
H. T. Witt, E. Scholdder, and P. Gräbert, FEBS Lett. 69, 272–276 (1976).
E. Scholdder, M. Rögner, and H. T. Witt, FEBS Lett. 138, 13–18 (1982).
E. Neumann, in Topic of Bioelectrochemistry and Bioenergetics ( G. Milasso, ed.) Wiley, New York (1981), Vol. 4, pp. 113–160.
E. Neumann, in Ions in Macromolecular and Biological Systems ( D. H. Everett and B. Vincent, eds.), Scientechnica, Bristol (1978), pp. 170–191.
A. Katchlsky and E. Neumann, Int. J. Neurosci. 3, 175–182 (1972).
K. Tsuji and E. Neumann, FEBS Lett. 128, 265–268 (1981).
K. Tsuji and E. Neumann, FEBS Lett. 128, 265–268 (1981).
D. Schallreuter, Ph.D. thesis, Konstanz and Martinsried (1982); E. Neumann, K. Tsuji, and D. Schallreuter in Biological Structures and Coupled Flows (A. Oplatka and M. Balaban, eds.), Academic, New York (1983), pp. 135–138.
M. Eigen and L. C. M. DeMaeyer, Tech. Org. Chem. 8 (2), 895–1054 (1963).
K. Bergmann, M. Eigen, and L. C. M. DeMaeyer, Ber. Bunsenges. Phys. Chem. 67, 819–826 (1963).
G. Schwarz, J. Phys. Chem. 71, 4021–4030 (1967).
L. Onsager, J. Chem. Phys. 2, 599–615 (1934).
H.-J. Nolte, T. L. Rosenberry, and E. Neumann, Biochemistry 19, 3705–3711 (1980).
A. Enokida, T. Okubo, and N. Ise, Macromolecules 13, 49–53 (1980).
E. Neumann and H. J. Nolte, Bioelectrochem. Bioenerg. 8, 89–101 (1981).
C. T. O’Konski and A. J. Haltner, J. Am. Chem. Soc. 79, 5634–5649 (1957).
M. Tricot and C. Houssier, in Polyelectrolytes ( K. C. Frisch, D. Klempner, and A. V. Patsis, eds.), pp. 43–90, Technomic, Westport (1976).
E. Fredericq and C. Houssier, Electric Dichroism and Electric Birefringence, Clarendon, Oxford (1973).
M. Eigen and G. Schwarz, Z. Phys. Chem. N.F. 4, 380–385 (1955).
M. Eigen and G. Schwarz, J. Coli. Sci. 12, 181–194 (1957).
M. Eigen and G. Schwarz, in Electrolytes ( B. Pesce, ed.), Pergamon, Oxford (1962), pp. 309–335.
C. T. O’Konski and N. C. Stellwagen, Biophys. J. 5, 607–613 (1965).
G. Schwarz and J. Seelig, Biopolymers 6, 1263–1277 (1968).
E. Neumann and A. Katchalsky, Proc. Natl. Acad. Sci. USA 69, 993–997 (1972).
E. Neumann, Angew. Chem. Intern. Ed. 12, 356–369 (1973).
K. Kikuchi and K. Yoshioka, Biopolymers 12, 2667–2679 (1973).
T. Yasunaga, T. Sano, K. Takahashi, H. Takenaka, and S. Ito, Chem. Lett. (Japan), 405–408 (1973).
A. Revzin and E. Neumann, Biophys. Chem. 2, 144–150 (1974).
D. Pörschke, Nucl. Acid. Res. 1, 1601–1618 (1974).
D. Pörschke, Biopolymers 15, 1917–1928 (1976).
K. Kikuchi and K. Yoshioka, Biopolymers 15, 583–587 (1976).
E. Neumann and K. Rosenheck, J. Membrane Biol. 10, 279–290 (1972).
U. Zimmermann, P. Scheurich, G. Pilwat, and R. Benz, Angew. Chem. 93, 332–351 (1981).
J. Teissie and T. Y. Tsong, Biochemistry 20, 1548–1554 (1981).
E. A. Guggenheim, Thermodynamics, 5th rev. ed., North-Holland, Amsterdam (1967); J. Phys. Chem. 33, 842 (1929).
J. G. Kirkwood and I. Oppenheim, Chemical Thermodynamics, McGraw-Hill, New York (1961).
K. Tsuji and E. Neumann, Biophys. Chem. 17, 153–163 (1983).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Plenum Press, New York
About this chapter
Cite this chapter
Neumann, E. (1986). Elementary Analysis of Chemical Electric Field Effects in Biological Macromolecules. In: Gutmann, F., Keyzer, H. (eds) Modern Bioelectrochemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2105-7_4
Download citation
DOI: https://doi.org/10.1007/978-1-4613-2105-7_4
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9246-3
Online ISBN: 978-1-4613-2105-7
eBook Packages: Springer Book Archive