Improvement in Exercise-Induced Diastolic Blood Pressure Changes by Diuretic Treatment

  • C. Montanari
  • A. Vergani
Chapter
Part of the Developments in Nephrology book series (DINE, volume 18)

Abstract

Antihypertensive drugs would not seem to be very useful in controlling BP variations caused by phisical activity. Not many studies have been carried out in this regard, with the exception of those relative to beta blocking agents; these, however, show that at submaximal levels of effort there are not any significant reduction in SBP and DBP, and, if there are, BP decreases are of a value almost identical to the differences between the resting BP before and after treatment. In other words, the slope of SBP and DBP in relationship to the changes in workload, tends to be substantially the same, or even becoming sharper after antihypertensive therapy. It is quite probable that there may be drugs capable of minimizing this tendency (1,2).

Keywords

Clonidine Metoprolol Spironolactone Indapamide Penbutolol 

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References

  1. 1.
    Lund-Johansen, P. and Bakke, O.M. Br. J. clin. Pharmac. 7: 169–174, 1979Google Scholar
  2. 2.
    Roja, M., Cumetti, C., Vergani, A., Montanari, C. and De Cristofaro, A. Drugs Exptl. Clin. Res. 11 (12): 851–860, 1985Google Scholar

Copyright information

© Martinus Nijhoff Publishing, Boston 1987

Authors and Affiliations

  • C. Montanari
    • 1
  • A. Vergani
    • 1
  1. 1.Department of CardiologyIstituti Clinici di PerfezionamentoMilanItaly

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