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The Diuretic Effects of Lithium Salts. Absence of Side Effects

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Diuretics: Basic, Pharmacological, and Clinical Aspects

Part of the book series: Developments in Nephrology ((DINE,volume 18))

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Abstract

Lithium salts are known to posses antidiuretic properties as antidiuretic hormone antagonists affecting adenyl cyclase and may be considered collecting duct diuretics.(1) Nevertheless, fear of potential nephrotoxicity(2) has limited their use in clinical practice and they have been used almost esclusively as antidepressants. The strict monitorization of psychiatric patients undergoing long term treatment with lithium carbonate enabled us to evaluate the diuretic properties and secondary effects of lithium salts.

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References

  1. Singer I, Kidney Int., 19:374–387, 1981.

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  2. Hansen H.E., Hestbech J, Sorensen J.L., Norgaarel K., Heilskov J. and Amdisen A., Q. J. Med. New Series, 192:577–591, 1979.

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  3. Bone S., Roose S.P., Dunner D.L. and Fieve R.R. Am. J. Psychiatry, 137: 103–104, 1980.

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  4. Wallin L., Allinq C. and Aurell M. Clin. Nephrol, 18:23–28, 1982.

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© 1987 Martinus Nijhoff Publishing, Boston

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Carreras, L. et al. (1987). The Diuretic Effects of Lithium Salts. Absence of Side Effects. In: Andreucci, V.E., Dal Canton, A. (eds) Diuretics: Basic, Pharmacological, and Clinical Aspects. Developments in Nephrology, vol 18. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2067-8_121

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  • DOI: https://doi.org/10.1007/978-1-4613-2067-8_121

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9227-2

  • Online ISBN: 978-1-4613-2067-8

  • eBook Packages: Springer Book Archive

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