Classification and Mechanism of Action of the Cardiac Inotropic Agents: An Overview

  • Adawia A. Alousi
Part of the Developments in Cardiovascular Medicine book series (DICM, volume 68)


The cardiac inotropic agents are substances that modify cardiac muscle contraction by acting directly on the myocardium (1). These agents could be categorized into two major classes; positive inotropic agents that stimulate cardiac muscle contraction such as the cardiac glycosides (2), the catecholamines (3) and the bipyridines (4), and negative inotropic agents that depress cardiac contraction such as the β-adrenergic blockers, the antiarrhythmics and the barbiturates (5).


Adenylate Cyclase Acute Heart Failure Cardiac Glycoside Inotropic Agent Digitalis Glycoside 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Martinus Nijhoff Publishing, Boston 1987

Authors and Affiliations

  • Adawia A. Alousi
    • 1
  1. 1.Molecular Cardiology UnitSterling-Winthrop Research InstituteRensselaerUSA

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