Abstract
IgA nephropathy is a distinct clinicopathologic entity originally described by Berger and Hinglais in 1968 [1]. IgA nephropathy (so-called Berger’s disease) is a more common type of glomerulonephritis in Japan than in France, the USA, and England [2–4]. Patients with IgA nephropathy account for more than 30% of patients with primary glomerulonephritis in Japan [4]. It is still unknown whether geographic and/or genetic factors are involved in the difference in the prevalence. Although IgA nephropathy is assumed to be an immune-complex-mediated glomerulonephritis, the antigens and exacerbating factors involved in this disease have not yet been identified. Moreover, there is no specific treatment of patients with IgA nephropathy. The purposes of this chapter are: (a) to describe the approach to pathogenesis and exacerbating factors, and (b) to describe the trials in new treatments for patients with IgA nephropathy.
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© 1987 Martinus Nijhoff Publishing, Boston
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Tomino, Y. (1987). The Future: A Japanese Perspective. In: Clarkson, A.R. (eds) IgA Nephropathy. Topics in Renal Medicine, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2039-5_16
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DOI: https://doi.org/10.1007/978-1-4613-2039-5_16
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9213-5
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