Animal Models of IgA Nephropathy
The traditional goal of experimental pathology is to elucidate pathogenesis and pathophysiology, thereby promoting understanding of a disease process, more accurate prognostication, and logical therapeutic intervention. While total satisfaction of these objectives is rare, even partial attainment assists in patient management and offers hope for greater future fulfillment. Limitations inherent in the study of experimental models include species differences between patients and experimental animals and the nearly inevitable variance of the model from the human disease.
KeywordsImmune Complex Bile Duct Ligation Secretory Component Mesangial Proliferation Mesangial Deposit
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