In Vitro Regulation of Dopaminergic Maturation
For several years, in spite of the fact that, according to what was known from studies on the peripheral nervous system, the existence of growth factors specific to central subpopulations of neurons was postulated, most experiments have focused on the survival and differentiation of brain cells in general. The central concern related to specificity was mainly restricted to the establishment of the neuronal circuitry: target recognition and synapse formation.
KeywordsDopamine Tyrosine Retina Choline Acetyl
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- Azmitia, E., Whitaker, P.M., Lauder, J., and Privat, A. (1983) Primary culture of dissociated fetal mesencephalic raphe: differential stimulation of serotonergic growth by target tissue. Soc. Neurosci. Abstr. 9:10.Google Scholar
- Berger, B., Di Porzio, U., Daguet, M.-C. Gay, M., Vigny, A., Glowinski, J., and Prochiantz, A. (1982) Long-term development of mesencephalic dopaminergic neurons of mouse embryos in dissociated primary cultures: morphological and histochemical characteristics. Neuroscience 7:193–205.PubMedCrossRefGoogle Scholar
- Björklund, A., Stenevi, U., Schmidt, R.H., Dunnett, S.B., and Gage, F.H. (1983) Intracerebral grafting of neuronal cell suspensions. I. Introduction and general methods of preparation. Acta. Physiol. Scand. Suppl. 522:1–7.Google Scholar
- Brundin, P., Isacson, O., Gage, F.H., and Björklund, A. (1986) Intracerebral grafting of dopamine-containing neuronal cell suspension: effect of mixing target and non-target cells. Dev. Brain Res. (in press).Google Scholar
- Denis-Donni, S., Glowinski, J., and Prochiantz, A. (1983) Specific influence of striatal target cells on the in vitro outgrowth of mesencephalic dopaminergic neurites: a morphological quantitative study. J. Neuroscience 3:2292–2299.Google Scholar
- Dreyfus, C.F., Gillies, M.A., Goldstein, M., and Black, I.B. (1985) The target hippocampus increases tyrosine hydroxylase and NE uptake in locus coeruleus in culture. Soc. Neurosci. Abstr. 11:947.Google Scholar
- Friedman, W.J., Dreyfus, C.F., Mwen, B.S., and Black, I.B. (1985) Depolarizing signals increase tyrosine hydroxylase development in cultured mouse substantia nigra. Soc. Neurosci. Abstr. 11:1142.Google Scholar
- Heller, A., Hoffmann, R.L., and Wainer, B. (1983) Enhancement of dopamine neuron survival and axonal proliferation by membranes from striatal target cells. Soc. Neurosci. Abstr. 9:10.Google Scholar
- Smalheiser, N.R., Peterson, E.R., and Crain, S.M. (1982) Neurites from mouse retina and dorsal root ganglion explant show specific behaviour within co-cultured tectum or spinal cord. Dev. Brain Res. 2:362–382.Google Scholar