Abstract
Isoenzymes in the human prostate gland are reviewed in depth by Dr. C.B. Brendler in the preceding chapter. The author focused his attention on the marker enzymes of clinical importance, i.e., acid and alkaline phosphatases, lactate dehydrogenase, creatine kinase and leucine aminopeptidase. Valuable information on the comparative aspect of prostatic and erythrocytic prostatic acid phosphatases was presented in Table I, in which the biochemical characteristics of the various forms of acid phosphatases were cited. It would, however, have perhaps been more beneficial to the readers if the author had provided similar tables for each of the other isoenzymes discussed. Nonetheless, this chapter successfully conveys the current status of isoenzymes in the human prostate gland, the general biochemical methodologies that have been used to characterize them, and the application of quantitative procedures for these isoenzymes pertinent to prostatic cancer. The author points out the potential and future challenge for urological researchers to discover markers that would have clinical value in diagnosing and staging of prostatic cancer in man, particularly in the early phases.
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© 1987 Martinus Nijhoff Publishers, Boston
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Chung, L.W.K. (1987). Editorial Comment. In: Ratliff, T.L., Catalona, W.J. (eds) Genitourinary Cancer. Cancer Treatment and Research, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2033-3_2
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DOI: https://doi.org/10.1007/978-1-4613-2033-3_2
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