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Isoenzymes in prostate cancer

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Genitourinary Cancer

Part of the book series: Cancer Treatment and Research ((CTAR,volume 34))

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Abstract

The human prostate is a rich source of both hydrolytic enzymes that are secreted in seminal plasma and of intracellular enzymes that regulate the metabolism of the glandular epithelium. Prostatic enzymatic activities may be altered both within the prostate and also in other tissues by neoplastic transformation and subsequent metastatic spread. Thus determination of enzymatic activities can be useful in the diagnosis and subsequent clinical evaluation of prostatic carcinoma. In the past, clinical enzymology of the prostate focused primarily on measurement of serum acid and alkaline phosphatase. More recently, however, other enzymes have attracted attention as potential biologic markers of prostatic carcinoma.

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Authors
  1. Charles B. Brendler
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Editors and Affiliations

  1. The Jewish Hospital of St. Louis, Washington University School of Medicine, 216 South Kingshighway Boulevard, P.O. Box 14109, 63178, St. Louis, MO, USA

    Timothy L. Ratliff Ph.D.

  2. The Jewish Hospital of St. Louis, Washington University School of Medicine, 63178, St. Louis, MO, USA

    William J. Catalona M.D.

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© 1987 Martinus Nijhoff Publishers, Boston

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Brendler, C.B. (1987). Isoenzymes in prostate cancer. In: Ratliff, T.L., Catalona, W.J. (eds) Genitourinary Cancer. Cancer Treatment and Research, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2033-3_1

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  • DOI: https://doi.org/10.1007/978-1-4613-2033-3_1

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9210-4

  • Online ISBN: 978-1-4613-2033-3

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