Hereditary colon cancer syndromes: polyposis and nonpolyposis (Lynch syndromes I & II) variants

  • Henry T. Lynch
  • Stephen J. Lanspa
  • Jane F. Lynch
Part of the Cancer Treatment and Research book series (CTAR, volume 33)


Colorectal cancer is second in incidence only to lung cancer in many of the western industrialized nations [1]. Its incidence has shown a steady increase since the turn of the century, a trend which has been attributed by some to changes in dietary patterns [2]. While environmental factors are of unquestionable significance in the etiology of colorectal cancer, the role of genetic factors, as in all forms of human diseases, must be considered. Unfortunately, in the case of colorectal cancer, with the exception of familial multiple adenomatous polyposis coli (FPC), the importance of genetics has been severely neglected. Recently, this entire subject has been extensively reviewed [3–5].


Colorectal Cancer Lynch Syndrome Adenomatous Polyp Colonic Polyp Hereditary Nonpolyposis Colorectal Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Martinus Nijhoff Publishers, Boston 1987

Authors and Affiliations

  • Henry T. Lynch
  • Stephen J. Lanspa
  • Jane F. Lynch

There are no affiliations available

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