Continuous Transcutaneous Monitoring pp 201-205 | Cite as
A Simple Method for HbF Analysis
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Abstract
It has been discussed by several authors1–4 that oxygen saturation (SO2) determined by CO-oxymeters are affected by fetal hemoglobin (HbF). This artefact depends on the wavelengths used to collect absorbance data and/ or the extinction coefficients used to calculate the hemoglobin derivatives. Increased HbF and oxyhemoglobin (HbO2) in human blood elevate the carboxyhemoglobin (HbCO) percentage and cause falsely underestimated SO2 values.
Keywords
Oxygen Saturation Fetal Blood Fetal Hemoglobin Pulse Oxymetry Draw Blood Sample
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References
- 1.A. Zwart, A. Buursma, B. Oeseburg and W. G. Zijlstra, Determination of hemoglobin derivatives with the IL 282 CO-oxymeter as compared with a manual spectrophotometric five-wavelength method, Clin Chem 27:1903 (1981)Google Scholar
- 2.P. J. H. Cornelissen, C .L. M. van Woensel, W. C. van Oel and P. A. de Jong, Correction factors for hemoglobin derivatives in fetal blood as measured with the IL 282 CO-oxymeter, Clin Chem 29:1555 (1983)Google Scholar
- 3.R. Huch, A. Huch, P. Tuchschmid, W. G. Zijlstra and A. Zwart, Carboxyhemoglobin concentration in fetal cord blood, Pediatrics 71:461 (1983)Google Scholar
- 4.M. S. Jennis and J. L. Peabody,Pulse oximetry-an alternative method for the assessement of oxygenation in newborn infants, Pediatrics in pressGoogle Scholar
- 5.P. Tuchschmid, Errors in the measurement of CO-hemoglobin in fetal blood by automated multicomponent analysis: cause and correction, This volumeGoogle Scholar
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© Plenum Press, New York 1987