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Perturbation of S-Adenosylhomocysteine and S-adenosylmethionine Levels, Inhibition of Histamine Metabolism in the Guinea Pig, by Nicotine

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Tobacco Smoking and Nicotine

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 31))

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Abstract

Previous work from our laboratory has shown that both (R-(+)-and S-(-)-nicotine enantiomers are capable of interacting with endogenous N-methyltransferase systems both in vitro and in vivo. This present study was designed to determine whether nicotine was capable of perturbing SAH and SAM levels in vivo, in guinea pig lung and liver.

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Authors and Affiliations

  1. College of Pharmacy and Graduate Center for Toxicology, University of Kentucky, Lexington, KY, USA

    C. Steven Godin, Abdul Al Houdi & Peter A. Crooks

Authors
  1. C. Steven Godin
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  2. Abdul Al Houdi
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  3. Peter A. Crooks
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, University of Kentucky, Lexington, Kentucky, 40536, USA

    William R. Martin

  2. Department of Medicine, Veterans Administration Medical Center University of Kentucky, Lexington, Kentucky, 40511, USA

    Glen R. Van Loon

  3. Department of Pharmacology College of Medicine, University of Kentucky, Lexington, Kentucky, 40536, USA

    Edgar T. Iwamoto

  4. The Tobacco and Health Research Institute, University of Kentucky, Lexington, Kentucky, 40536, USA

    Edgar T. Iwamoto

  5. Tobacco and Health Research Institute, University of Kentucky, Lexington, Kentucky, 04546-0236, USA

    Layten Davis (Director) (Director)

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© 1987 Plenum Press, New York

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Godin, C.S., Al Houdi, A., Crooks, P.A. (1987). Perturbation of S-Adenosylhomocysteine and S-adenosylmethionine Levels, Inhibition of Histamine Metabolism in the Guinea Pig, by Nicotine. In: Martin, W.R., Van Loon, G.R., Iwamoto, E.T., Davis, L. (eds) Tobacco Smoking and Nicotine. Advances in Behavioral Biology, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1911-5_41

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  • DOI: https://doi.org/10.1007/978-1-4613-1911-5_41

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9063-6

  • Online ISBN: 978-1-4613-1911-5

  • eBook Packages: Springer Book Archive

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