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Stereoselectivity of Nicotine’s Central Effects and Its Relationship to Pain and Cardiovascular Function

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Tobacco Smoking and Nicotine

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 31))

Abstract

Nicotine produces a wide range of effects on the central nervous system which include convulsions (1), prostration (2), antinociception (3–11), release of antidiuretic hormone (12,13), tremors (13,14), as well as alterations in behavior (15,16), motor performance (3, 10, 17–19), gastric acid secretion (20–22), the cardiovascular system (7,23–30), learning (31), etc. The mechanisms by which nicotine produces these myriad effects have not been fully elucidated. Numerous studies have been carried out in an effort to characterize the effects of nicotine on central neurotransmitter functionality, as reviewed by Aceto and Martin (32) as well as contributors in this volume.

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Authors and Affiliations

  1. Department of Pharmacology and Toxicology Medical College of Virginia, Virginia Commonwealth University, Richmond, VA, 23298, USA

    Billy R. Martin

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Editors and Affiliations

  1. Department of Pharmacology, University of Kentucky, Lexington, Kentucky, 40536, USA

    William R. Martin

  2. Department of Medicine, Veterans Administration Medical Center University of Kentucky, Lexington, Kentucky, 40511, USA

    Glen R. Van Loon

  3. Department of Pharmacology College of Medicine, University of Kentucky, Lexington, Kentucky, 40536, USA

    Edgar T. Iwamoto

  4. The Tobacco and Health Research Institute, University of Kentucky, Lexington, Kentucky, 40536, USA

    Edgar T. Iwamoto

  5. Tobacco and Health Research Institute, University of Kentucky, Lexington, Kentucky, 04546-0236, USA

    Layten Davis (Director) (Director)

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© 1987 Plenum Press, New York

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Martin, B.R. (1987). Stereoselectivity of Nicotine’s Central Effects and Its Relationship to Pain and Cardiovascular Function. In: Martin, W.R., Van Loon, G.R., Iwamoto, E.T., Davis, L. (eds) Tobacco Smoking and Nicotine. Advances in Behavioral Biology, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1911-5_19

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  • DOI: https://doi.org/10.1007/978-1-4613-1911-5_19

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