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Stimulation of Suppressor Cell Activity by Cefadroxil

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Abstract

The interaction between antimicrobial agents and the human immune system is still poorly understood. However, many in vitro effects of antibiotics have been reported in experimental systems (7,15). Some antibiotics have been shown to decrease some immunological parameters such as neutrophil functions (8), lymphocyte responsiveness to polyclonal mitogens (2,3,14), or natural killer cell activity (9).

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References

  1. P. Aubas, B. Cosso, P. Godard, F. B. Michel, and J. Clot, Decreased suppressor cell activity of alveolar macrophages in bronchial asthma, Am. Rev. Respir. Pis., 130:875 (1984).

    CAS  Google Scholar 

  2. G. Banck and A. Forsgren, Antibiotics and suppression of lymphocyte function in vitro. Antimicrobiol. Agents chemother., 16:554 (1979).

    CAS  Google Scholar 

  3. E. A. Chaperon and W. E. Sanders, Suppression of lymphocyte response by cephalosporins, Inf. Immun., 19:451 (1978).

    Google Scholar 

  4. E. A. Chaperon, Suppression of lymphocytes by cephalosporins, in: “The Influence of Antibiotics on the Host-Parasite Relationship,” J. Eickenberg, H. Hahn and W. Opferkuch, eds., Springer-Verlag, Berlin (1982).

    Google Scholar 

  5. J. Clot, E. Charmasson, and J. Brochier, Age-dependent changes of human blood lymphocytes subpopulations, Clin. Exp. Immunol., 32:346 (1978).

    PubMed  CAS  Google Scholar 

  6. A. L. De Week, Penicillins and cephalosporins, in: “Allergic Reactions to Drugs,” A. L. De Week and H. Bundgaard, eds., Springer-Verlag, Berlin (1983).

    Google Scholar 

  7. R. Finch, Immunomodulating effects of antimicrobial agents, J.Antimicrobial. Chemother., 6:691 (1980).

    Article  CAS  Google Scholar 

  8. A. Forsgren, D. Schmeling, and P. G. Quie, Effect of tetracycline on the phagocytic function of human leucocytes, J. Infect. Pis., 130:412 (1974).

    Article  CAS  Google Scholar 

  9. D. H. B. Goh and A. Ferrante, In vitro inhibition of natural killer cell activity by doxycycline, Int. J. Immunopharmac., 6:51 (1984).

    Article  CAS  Google Scholar 

  10. J. S. Goodwin and J. Ceuppens, Regulation of the immune response by prostaglandin, J. Clin. Immunol., 3:295 (1983).

    Article  PubMed  CAS  Google Scholar 

  11. K. Ishizaka, Regulation of IgE synthesis, Ann. Rev. Immunol., 2:159 (1984).

    Article  CAS  Google Scholar 

  12. J. I. Kurland and R. Bockman, Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages, J. Exp. Med., 147:952 (1978).

    Article  PubMed  CAS  Google Scholar 

  13. E. L. Larsson, Mechanism of T cell activation. II. Antigen and lectin-dependent acquisition of responsiveness to TCGF is a nonmitogenic, active response of resting T cells, J. Immunol., 126:1323 (1981).

    PubMed  CAS  Google Scholar 

  14. Y. H. Thong and A. Ferrante, Inhibition of mitogen-induced human lymphocyte proliferative responses by tetracycline analogues, Clin. Exp. Immunol., 35:443 (1979).

    PubMed  CAS  Google Scholar 

  15. Y. H. Thong and A. Ferrante, Effect of tetracycline treatment on immunological responses in mice, Clin. Exp. Immun., 39:728 (1980).

    PubMed  CAS  Google Scholar 

  16. T. Watanabe, M. Kimoto, S. Maruyama, T. Kishimoto, and Y. Yamamura, Regulation of antibody response in different immunoglobulin classes, V. Establishment of T cell hybrid cell line secreting IgE class-specific suppressor factor, J. Immunol., 121:2113 (1978).

    PubMed  CAS  Google Scholar 

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© 1987 Plenum Press, New York

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Clot, J.P., Pelous, C. (1987). Stimulation of Suppressor Cell Activity by Cefadroxil. In: Szentivanyi, A., Friedman, H., Gillissen, G. (eds) Antibiosis and Host Immunity. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1901-6_27

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  • DOI: https://doi.org/10.1007/978-1-4613-1901-6_27

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9058-2

  • Online ISBN: 978-1-4613-1901-6

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