Abstract
The diabetes insipidus syndrome is characterized by the inability to concentrate urine or conserve water. The term insipidus reflects the pale, almost colorless waterlike urine excreted by patients in the fully expressed syndrome. Diabetes insipidus results from either impaired synthesis and release of vasopressin (central diabetes insipidus, neurogenic diabetes insipidus, vaso-pressin-sensitive diabetes insipidus) or peripheral resistance to the actions of vasopressin at the level of its target organ, the renal tubules (nephrogenic diabetes insipidus). Regardless of the type, the resulting disturbances in water metabolism are identical, with the continuous production of extremely large volumes of very dilute urine. Diabetes insipidus can be partial or complete, temporary or permanent.
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Kannan, C.R. (1987). Diabetes Insipidus. In: The Pituitary Gland. Clinical Surveys in Endocrinology, vol 1. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1849-1_20
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DOI: https://doi.org/10.1007/978-1-4613-1849-1_20
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