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Retrotransposition in Yeast

  • Gerald R. Fink
Part of the New Horizons in Therapeutics book series (NHTH)

Abstract

The Ty elements of yeast are repetitive chromosomal elements capable of transposition, a nonhomologous recombination event that leads to insertion of an element at a new chromosomal site. The structure of Ty elements is similar to that of the endogenous proviruses found in vertebrates (Clare and Farabaugh, 1985; Mount and Rubin, 1985). Each element contains a large central portion of approximately 5.2 kilobases flanked by direct repeats of about 330 base pairs (bp) called 5 or long terminal repeat (LTR) sequences (Fig. 1). Ty elements are repeated about 30–40 times per haploid genome and are found in variable chromosomal locations in different strains.

Keywords

Neurospora Crassa Rous Sarcoma Virus GALl Promoter Active Copy Donor Element 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Gerald R. Fink
    • 1
  1. 1.Whitehead Institute for Biomedical ResearchMassachusetts Institute of TechnologyCambridgeUSA

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