Retrotransposition in Yeast

  • Gerald R. Fink
Part of the New Horizons in Therapeutics book series (NHTH)


The Ty elements of yeast are repetitive chromosomal elements capable of transposition, a nonhomologous recombination event that leads to insertion of an element at a new chromosomal site. The structure of Ty elements is similar to that of the endogenous proviruses found in vertebrates (Clare and Farabaugh, 1985; Mount and Rubin, 1985). Each element contains a large central portion of approximately 5.2 kilobases flanked by direct repeats of about 330 base pairs (bp) called 5 or long terminal repeat (LTR) sequences (Fig. 1). Ty elements are repeated about 30–40 times per haploid genome and are found in variable chromosomal locations in different strains.


Neurospora Crassa Rous Sarcoma Virus GALl Promoter Active Copy Donor Element 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Gerald R. Fink
    • 1
  1. 1.Whitehead Institute for Biomedical ResearchMassachusetts Institute of TechnologyCambridgeUSA

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