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Brief History of the Role of Nutrition in Carcinogenesis

  • Lionel A. Poirier

Abstract

That diet exerts an influence on the development of tumors in humans and in experimental animals has been recognized for over 60 years. From 1940 to 1960, a number of essential nutrients were shown to significantly alter the carcinogenic activities of specific polycyclic aromatic hydrocarbon and aromatic amine and aminoazo dye carcinogens. Diet has been shown to modify the carcinogenic process at many stages. Since 1970, the number of known interactions between carcinogens and essential nutrients has increased markedly. It is hoped that this volume will provide a comprehensive evaluation increasing our understanding of the multiple effects of the essential nutrients on carcinogenesis.

Keywords

Polycyclic Aromatic Hydrocarbon Aromatic Amine Essential Nutrient Carcinogenic Activity Cheek Pouch 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

DAB

N,N-dimethyl-4-aminoazobenzene

AAF

2-acetylamino-fluorene

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Copyright information

© Plenum Press, New York 1986

Authors and Affiliations

  • Lionel A. Poirier
    • 1
  1. 1.Nutrition and Metabolism Section, Laboratory of Comparative CarcinogenesisNCI-Frederick Cancer Research FacilityFrederickUSA

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