Abstract
Polymer surface analysis is essential for the study of biomaterials because the ultimate biological response to implanted materials depends on what proteins and cells “see” at the interface. Ideally, we would like to routinely correlate the characteristics of the surface structure with the events that comprise the observed biological response. Electron spectroscopy for chemical analysis (ESCA) has been found to be useful in enhancing our understanding of biomaterials surfaces and has demonstrated the potential to generate data that might be correlated with complex biological interactions.
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References
B. Ratner, in: Treatise on Clean Surface Technology (K.L., Mittal, ed.), p., Plenum Press, New York (1985). (in press)
B.D. Ratner, Analysis of surface contaminants on intra-ocular lenses, Arch. Ophthal. 101, 1434–1438(1983).
B.D. Ratner, J.J. Rosen, A.S. Hoffman and L.H. Scharpen, in: Surface Contamination (K.L., Mittal, ed.), Vol. 2, pp.669–686, Plenum Publishing Corp., New York (1979).
B.D. Ratner, P.K. Weathersby, A.S. Hoffman, M.A. Kelly and L.H. Scharpen, Radiation-grafted hydrogels for biomaterial applications as studied by the ESCA technique, J. Appl. Polym. Sci. 22, 643–664(1978).
F.J. Holly and M.F. Refojo, in: Hydrogels for Medical and Related Applications, ACS Symposium Series (J.D., Andrade, ed.), Vol. 31, pp.252–266, American Chemical Society, Washington, DC (1976).
D.S. Everhart and C.N. Reilley, The effects of functional group mobility on quantitative ESCA of plasma modified polymer surfaces, Surf. Interf. Anal. 3, 126–133(1981).
D.S. Everhart and C.N. Reilley, Polymer functional group mobility II. Partition of ion pairs between hydrophobic and hydrophilic phases of plasma oxidized polyethylene, Surf. Interf, Anal. 3, 258–268(1981).
J.D. Andrade, S.M. Ma, R.N. King and D.E. Gregonis, Contact angles at the solid-water interface, J. Coll. Interf. Sci. 72, 488–494(1979).
Y.C. Ko, B.D. Ratner and A.S. Hoffman, Characterization of hydrophilic-hydrophobic polymeric surfaces by contact angle measurements, J. Coll. Interf. Sci. 82, 25–37(1981).
R.G. Azrak, Surface property variations in melt-formed thermoplastics, J. Coll. Interf. Sci. 47, 779–794(1974).
B.D. Ratner, in: Surface and Interfacial Aspects of Biomedical Polymers(J.D., Andrade, ed.), Vol. 1, pp.373–394, Plenum Publishing Corp., New York (1985).
R.W. Paynter, B.D. Ratner and H.R. Thomas, in: Polymers as Biomaterials(S.W., Shalaby, A.S., Hoffman, B.D., Ratner and T.A., Horbett, eds.), pp.121–133, Plenum Publishing Co., New York (1984).
J.J. O’Malley, H.R. Thomas and G.M. Lee, Surface studies on multicomponent polymer systems by X-ray photoelectron spectroscopy. Polystyrene/poly(ethylene oxide) triblock copolymers, Macromolecules 12, 996–1001(1979).
C.B. Hu and C.S.P. Sung, Surface chemical composition-depth profile of polyether polyurethaneureas as studied by FTIR and ESCA, Polym. Prepr., Am. Chem. Soc., Div. Polym. Chem. 21, 156–158(1980).
D. Briggs, D.M. Brewis and M.B. Konieczko, X-ray photoelectron spectroscopy studies of polymer surfaces, J. Mater. Sci. 14, 1344–1348 (1979).
D.T. Clark, W.J. Feast, W.K.R. Musgrave and I. Ritchie, Applications of ESCA to polymer chemistry. Part VI. Surface fluorination of polyethylene. Application of ESCA to the examination of structure as a function of depth, J. Polym. Sci., Polym. Chem. Ed. 13, 857–890(1975).
R. Chujo, T. Nishi, Y. Sumi, T. Adachi, H. Naito and H. Frentzel, Vertical distribution of components in a polymer blend with the aid of the secondary ion mass spectroscopy, J. Polym. Sci., Polym. Lett. Ed. 21, 487–494(1983).
B.D. Ratner, Surface characterization of biomaterials by electron spectroscopy for chemical analysis, Ann. Biomed. Eng. 11, 313–336(1983).
S.R. Hanson, L.A. Harker, B.D. Ratner and A.S. Hoffman, in: Biomaterials 1980; Advances in Biomaterials(G.D., Winter, D.F., Gibbons and H., Plenk Jr., eds.), Vol. 3, pp.519–530, John Wiley and Sons Ltd., Chichester, England (1982).
S.R. Hanson, L.A. Harker, B.D. Ratner and A.S. Hoffman, In vivo evaluation of artificial surfaces with a nonhuman primate model of arterial thrombosis, J. Lab. Clin. Med. 95, 289–304(1980).
D. Briggs(ed.), Handbook of X-ray and Ultraviolet Photo-electron Spectroscopy, Heyden & Sons, Ltd., London (1977).
T.A. Carlson, Photoelectron and Auger Spectroscopy, Plenum Press, New York (1975).
P.K. Ghosh, Introduction to Photoelectron Spectroscopy, John Wiley &Sons, New York (1983).
K. Siegbahn, C. Nordling, A. Fahlman, R. Nordberg, K. Hamrin, J. Hedman, G. Johansson, T. Bergmark, S.E. Karlsson, I. Lindgren and B. Lindberg, ESCA: Atomic, molecular and solid state structure studied by means of electron spectroscopy, Nova Acta Regiae Societatis Scientiarum Upsaliensis, Ser.IV 20, 5–282(1967).
K. Siegbahn, Electron spectroscopy for atoms, molecules, and condensed matter, Science 217, 111–121(1982).
N. Winograd and S.W. Gaarenstroom, in: Physical Methods in Modern Chemical Analvsis(T., Kuwana, ed.), Vol. 2, pp.115–169, Academic Press, New York (1980).
D. Briggs, New developments in polymer surface analysis, Polymer 25, 1379–1391(1985).
D.T. Clark, in: Polymer Surfaces(D.T., Clark and W.J., Feast, eds.), pp.309–351, Wiley, J. &Sons, Chichester (1978).
A. Dilks, in: Electron Spectroscopy: Theory, Techniques, and Applications(A.D., Baker and C.R., Brundle, eds.), Vol. 4, pp.277–359, Academic Press, London (1981).
B.D. Ratner and B.J. McElroy, in: Spectroscopy in the Biomedical Sciences(R.M., Gendreau, ed.), p., CRC Press, Boca Raton, Fl (1985). (in press)
J.D. Andrade(ed.), Surface and Interfacial Aspects of Biomedical Polymers, Plenum Press, New York (1985).
D. Briggs and M.P. Seah(eds.), Practical Surface Analysis, John Wiley &Sons, Chichester (1983).
D.T. Clark, Advances in ESCA applied to polymer characterization, Pure &Appl. Chem. 54(2), 415–438(1982).
M.P. Seah, The quantitative analysis of surfaces by XPS: A review, Surf. Interf. Anal. 2, 222–239(1980).
R.S. Swingle and W.M. Riggs, ESCA, Crit. Rev. Anal. Chem. 5, 267–321 (1975).
CD. Wagner, W.M. Riggs, L.E. Davis and J.F. Moulder, Handbook of X-Ray Photoelectron Spectroscopy, Perkin-Elmer Corporation, Eden Prairie, MN (1979).
R.W. Paynter, Modification of the Beer-Lambert equation for application to concentration gradients, Surf. Interf. Anal. 3, 186–187(1981).
D. Cohn, A.S. Hoffman, B.D. Ratner and Y. Haque, Plasma-treated surfaces for biomedical applications: compositional analysis, Abstracts of the 2nd International Conference on Polymers in Medicine, Capri, Italy, June 3–7, 1985, C9.
D.T. Clark, J. Peeling and J.J. O’Malley, Application of ESCA to polymer chemistry. VIII. Surface structures of AB block copolymers of polydimethylsiloxane and polystyrene, J. Polym. Sci., Polym. Chem Ed. 14, 543–551(1976).
H.R. Thomas and O’Malley, Surface studies on multicomponent polymer systems by X-ray photoelectron spectroscopy: Polystyrene/poly(ethylene oxide) homopolymer blends, Macromolecules 14, 1316–1320(1981).
S.C. Yoon and B.D. Ratner, Surface structure of segmented polyetherurethanes and polyetherurethaneureas with various perfluoro chain extenders. An x-ray photoelectron spectroscopic investigation, Macromolecules. (submitted)
J. Blackwell, M.R. Nagarajan and T.B. Hoitink, Structure of polyurethane elastomers: effect of chain extender length on the structure of MDI/diol hard segments, Polymer 23, 950–956(1982).
J. Blackwell and M.R. Nagarajan, Conformational analysis of poly(MDI-butandiol) hard segment in polyurethane elastomers, Polymer 22, 202–208 (1981).
J. Blackwell, J.R. Quay, M.R. Nagarajan, L. Born and H. Hespe, Molecular parameters for the prediction of polyurethane structures, J. Polym. Sci., Polym. Phys. Ed. 22, 1247–1259(1984).
V. Sa Da Costa, D. Brier-Russell, E.W. Salzman and E.W. Merrill, ESCA studies of polyurethanes: blood platelet activation in relation to surface composition, J. Coll. Interf. Sci. 80, 445–452(1981).
J.P. Fischer, P. Fuhge, K. Burg and N. Heimburger, Methoden zur Herstellung und Charakterisierung von Kunststoffen mit verbesserter Blutvertraglichkeit, Angew. Makromol. Chem. 105, 131–165(1982).
S.K. Chang, O.S. Hum, M.A. Moscarello, A.W. Neumann, W. Zingg, M.J. Leutheusser and B. Ruegsegger, Platelet adhesion to solid surfaces. The effect of plasma proteins and substrate wettability, Med. Progr. Technol. 5, 57–66(1977).
D.J. Lyman, W.M. Muir and I.J. Lee, The effect of chemical structure and surface properties of polymers on the coagulation of blood. I. Surface free energy efects, Trans. Am. Soc. Artif. Int. Organs 11, 301–306(1965).
N. Mohandas, R.M. Hochmuth and E.E. Spaeth, Adhesion of red cell to foreign surfaces in the presence of flow, J. Biomed. Mater. Res. 8, 119–136 (1974).
H. Yasuda, B.S. Yamanashi and D.P. Devito, The rate of adhesion of melanoma cells onto nonionic polymer surfaces, J. Biomed. Mater. Res. 12, 701–706(1978).
B.D. Ratner and R.W. Paynter, in: Polyurethanes in Biomedical Engineering, Progress in Biomedical Engineering(H., Planck, G., Egbers and I., Syre, eds.), Vol. 1, pp.41–68, Elsevier, Amsterdam (1984).
M.D. Lelah, L.K. Lambrecht, B.R. Young and S.L. Cooper, Physiochemical characterization and in vivo blood tolerability of cast and extruded biomer, J. Biomed. Mater. Res. 17, 1–22(1983).
G. Binning and H. Rohrer, Scanning tunneling microscopy, Physica 127B, 37–45(1984).
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Ratner, B.D. (1986). ESCA for the Study of Biomaterial Surfaces. In: Chiellini, E., Giusti, P., Migliaresi, C., Nicolais, L. (eds) Polymers in Medicine II. Polymer Science and Technology, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1809-5_2
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DOI: https://doi.org/10.1007/978-1-4613-1809-5_2
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