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Proteins pp 581-598 | Cite as

EscherichiaColi ADPglucose Synthetase Substrate-Inhibitor Binding Sites Studied by Site(S) Directed Chemical Modification and Mutant Enzyme Characterization

  • Young Moo Lee
  • Charles E. Larsen
  • Jack Preiss

Abstract

ADPglucose synthetase catalyzes the synthesis of ADPglucose from α-glucose 1-P and ATP (reaction 1) (1) ATP + a-glucose 1-P ⇌ ADPglucose + PPi ADPglucose is the glucosyl donor for starch synthesis in plants and for glycogen synthesis in bacteria and ADPglucose synthetase has been shown to be the major regulatory enzyme for a 1,4 glucan sythesis in bacteria as well as in plants.

Keywords

Activator Binding Site Incorporated Peptide CNBr Peptide Photoaffinity Probe Bacterial Glycogen 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Young Moo Lee
    • 1
  • Charles E. Larsen
    • 1
  • Jack Preiss
    • 1
  1. 1.Department of BiochemistryMichigan State UniversityEast LansingUSA

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